P
Patrizia Romualdi
Researcher at University of Bologna
Publications - 146
Citations - 3105
Patrizia Romualdi is an academic researcher from University of Bologna. The author has contributed to research in topics: Dynorphin & Opioid. The author has an hindex of 26, co-authored 138 publications receiving 2745 citations. Previous affiliations of Patrizia Romualdi include Uniformed Services University of the Health Sciences & University of Verona.
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Journal ArticleDOI
Chronic delta 9-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates.
Tiziana Rubino,Daniela Viganò,Natalia Realini,C. Guidali,Daniela Braida,Valeria Capurro,Chiara Castiglioni,Francesca Cherubino,Patrizia Romualdi,Sanzio Candeletti,Mariaelvina Sala,Daniela Parolaro +11 more
TL;DR: The results suggest that heavy cannabis consumption in adolescence may induce subtle alterations in the emotional circuit in female rats, ending in depressive-like behavior, whereas male rats show altered sensitivity to rewarding stimuli.
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Selective DNA Methylation of BDNF Promoter in Bipolar Disorder: Differences Among Patients with BDI and BDII
Claudio D'Addario,Bernardo Dell'Osso,Maria Carlotta Palazzo,Beatrice Benatti,L. Lietti,E. Cattaneo,Daniela Galimberti,Chiara Fenoglio,Francesca Cortini,Elio Scarpini,Beatrice Arosio,Andrea Di Francesco,Manuela Di Benedetto,Patrizia Romualdi,Sanzio Candeletti,Daniela Mari,Luigi Bergamaschini,Nereo Bresolin,Mauro Maccarrone,A. Carlo Altamura +19 more
TL;DR: Findings suggest selective changes in DNA methylation of BDNF promoter in subjects with BD type II and highlight the importance of epigenetic factors in mediating the onset and/or susceptibility to BD, providing new insight into the mechanisms of gene expression.
Journal ArticleDOI
Substance P is diminished and vasoactive intestinal peptide is augmented in psoriatic lesions and these peptides exert disparate effects on the proliferation of cultured human keratinocytes.
Carlo Pincelli,Fabrizio Fantini,Patrizia Romualdi,Cinzia Sevignani,G. Lesa,Luisa Benassi,Alberto Giannetti +6 more
TL;DR: The imbalance of cutaneous VIP and SP and their disparate effects on the proliferation of normal human keratinocytes in culture would suggest that these peptides are involved in the pathogenesis of psoriasis and may exert different modulatory activities in the mechanisms underlying the psoriatic lesion.
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Blockade of Nociceptin/Orphanin FQ Transmission Attenuates Symptoms and Neurodegeneration Associated with Parkinson's Disease
Matteo Marti,Flora Mela,Martina Fantin,Silvia Zucchini,Jeffrey M. Brown,Jassir Witta,Manuela Di Benedetto,Beata Buzas,Rainer K. Reinscheid,Severo Salvadori,Remo Guerrini,Patrizia Romualdi,Sanzio Candeletti,Michele Simonato,Brian M. Cox,Michele Morari +15 more
TL;DR: Evidence suggesting that endogenous N/OFQ may contribute to Parkinson's disease is presented and it is proposed that NOP receptor antagonists may represent a novel approach for combined (symptomatic and neuroprotective) therapy of Parkinson’s disease.
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The effects of nonsteroidal anti-inflammatory drugs on clinical outcomes, synovial fluid cytokine concentration and signal transduction pathways in knee osteoarthritis. A randomized open label trial.
Luca Gallelli,Olimpio Galasso,Daniela Falcone,S. R. Southworth,Marta Greco,Valeria Ventura,Patrizia Romualdi,A. Corigliano,Rosa Terracciano,Rocco Savino,Elio Gulletta,Giorgio Gasparini,G. De Sarro +12 more
TL;DR: Short-term NSAID treatment improves the patient disease-specific quality of life with a parallel decrease in pro-inflammatory synovial fluid cytokine levels in knee OA.