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Nereo Bresolin

Researcher at University of Milan

Publications -  604
Citations -  24253

Nereo Bresolin is an academic researcher from University of Milan. The author has contributed to research in topics: Population & Gene. The author has an hindex of 78, co-authored 595 publications receiving 22221 citations. Previous affiliations of Nereo Bresolin include University College London & University of Southern California.

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Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication.

TL;DR: Examination of mtDNA revealed high copy point mutations at specific positions in the control region for replication of human fibroblast mtDNA from normal old, but not young, individuals.
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Disorders of cognitive and affective development in cerebellar malformations.

TL;DR: The overall favourable evolution with an onset of skills in advanced age in a consistent subset of subjects suggests that individual follow-ups should be performed in order to monitor the quality and stability of impairments and acquired abilities over time.
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In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria.

TL;DR: A severe mitochondrial protein synthesis defect in myoblasts from a patient with mitochondrial myopathy was transferred with myoblast mitochondria into two genetically unrelated mitochondrial DNA-less human cell lines, pointing to an mtDNA alteration as being responsible and sufficient for causing the disease.
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Identification of a Primitive Brain–Derived Neural Stem Cell Population Based on Aldehyde Dehydrogenase Activity

TL;DR: The ALDH expression assay is an effective method for direct identification of NSCs, and improvement of the stem cell isolation protocol may be useful in the development of a cell‐mediated therapeutic strategy for neurodegenerative diseases.