Patrizia Stifanelli

TL;DR: In this article, the authors conducted a microarray study to identify genes and pathways differentially modulated in peripheral blood leukocytes isolated from 12 immunoglobulin A nephropathy (IgAN) patients and 8 healthy controls.

TL;DR: A defect in antigen handling in peripheral blood mononuclear cells of IgAN patients with a specific increase of CX3CR1 is found, which suggests a predisposition for cytotoxic cell extravasation only in patients with recurrent gross hematuria.

TL;DR: The data suggest that MPA directly induces expression of neutral endopeptidase, which may reduce proteinuria and slow the progression of renal damage in kidney transplant recipients.

TL;DR: This paper compared three regularized methods of covariance selection for the inference of gene regulatory networks, and found that ℓ(2C) outperformed the other two methods having the most predictive partial correlation estimates and the highest values of sensitivity to infer conditional dependencies between genes even when a few number of observations was available.

TL;DR: Simulation work focuses on the implementation of a new approach for MPI reconstruction: it is called hybrid x-space (HXS), representing a combination of the previous methods, based on XS reconstruction, which requires the knowledge of the FFP position and velocity at each time instant.