P
Paul J. Jenkins
Researcher at St Bartholomew's Hospital
Publications - 84
Citations - 4805
Paul J. Jenkins is an academic researcher from St Bartholomew's Hospital. The author has contributed to research in topics: Acromegaly & Cancer. The author has an hindex of 39, co-authored 79 publications receiving 4568 citations. Previous affiliations of Paul J. Jenkins include Queen Mary University of London.
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Journal ArticleDOI
Comparison of Somatostatin Analog and Meta-Iodobenzylguanidine Radionuclides in the Diagnosis and Localization of Advanced Neuroendocrine Tumors
Gregory Kaltsas,Márta Korbonits,E. Heintz,J. J. Mukherjee,Paul J. Jenkins,Shern L. Chew,Rodney H. Reznek,John P Monson,G. M. Besser,R. Foley,Keith E. Britton,Ashley B. Grossman +11 more
TL;DR: Scintigraphy with [(111)In]pentetreotide detects more metastatic lesions than [(123)I]MIBG in patients with carcinoid and pancreatic islet cell tumors and medullary thyroid carcinomas; the radionuclides may exert a complementary role in the detection and treatment of neuroendocrine tumors in occasional patients.
Journal ArticleDOI
Acromegaly, colonic polyps and carcinoma
Paul J. Jenkins,Peter D. Fairclough,Toby Richards,David G. Lowe,John R. T. Monson,Ashley B. Grossman,John A.H. Wass,Michael Besser +7 more
TL;DR: The prevalence of carcinoma, premalignant tubulovillous adenomas and hyperplastic colonic polyps in a large cohort of patients with acromegaly is evaluated.
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Hypothalamo-pituitary abnormalities in adult patients with langerhans cell histiocytosis: clinical, endocrinological, and radiological features and response to treatment.
Gregory Kaltsas,T. B. Powles,Jane Evanson,Piers N. Plowman,J. E. Drinkwater,Paul J. Jenkins,John P Monson,G. M. Besser,Ashley B. Grossman +8 more
TL;DR: In adult patients with hypothalamic LCH and DI, anterior pituitary hormonal deficiencies developed in 8 of 12 patients; these occurred over the course of 20 yr; these were frequently accompanied by structural changes of the HPA, although these were often subtle in nature.
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Outcome of transsphenoidal surgery for acromegaly using strict criteria for surgical cure
R. Sheaves,Paul J. Jenkins,P. Blackburn,A. H. Huneidi,F. Afshar,S. Medbak,Ashley B. Grossman,G. M. Besser,J. A. H. Wass +8 more
TL;DR: The results of transsphenoidal pituitary surgery for acromegaly were analyzed to assess the longer‐term outcome for patients not offered further treatment when post‐operative levels of GH < 5 mU/l were achieved.
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Conventional pituitary irradiation is effective in lowering serum growth hormone and insulin-like growth factor-I in patients with acromegaly.
TL;DR: In this, the largest series reported, conventional pituitary irradiation is shown to be an effective and safe means of reducing both serum GH and IGF-I concentrations in patients with acromegaly.