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Paul Lewis
Researcher at Oregon Health & Science University
Publications - 22
Citations - 3695
Paul Lewis is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Virus & Viral load. The author has an hindex of 15, co-authored 20 publications receiving 3434 citations. Previous affiliations of Paul Lewis include University of Nairobi & Fred Hutchinson Cancer Research Center.
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Journal ArticleDOI
A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells
Michael Bukrinsky,Sheryl Haggerty,M. P. Dempsey,N. P. Sharova,Alexei A. Adzhubei,L Spitz,Paul Lewis,David S. Goldfarb,Michael Emerman,Mario Stevenson +9 more
TL;DR: HIV-1 mutants containing amino-acid substitutions in this nuclear localization signal integrate and replicate within dividing but not growth-arrested cells, and thus display a phenotype more representative of an onco-retrovirus.
Journal ArticleDOI
Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus.
Paul Lewis,Michael Emerman +1 more
TL;DR: It is suggested that mitosis is necessary for nuclear entry of MuLV, but not human immunodeficiency virus, unintegrated proviral DNA.
Journal ArticleDOI
Human immunodeficiency virus infection of cells arrested in the cell cycle.
TL;DR: HIV infection of non‐dividing cells distinguishes lentiviruses from other retroviruses and is likely to be important in the natural history of HIV infection.
Journal ArticleDOI
Symptomatic Acute Myocarditis in 7 Adolescents After Pfizer-BioNTech COVID-19 Vaccination.
Mayme Marshall,Ian Ferguson,Paul Lewis,Preeti Jaggi,Christina Gagliardo,Christina Gagliardo,James Stewart Collins,Robin Shaughnessy,Rachel Caron,Cristina Fuss,Kathleen Jo E. Corbin,Leonard Emuren,Erin Faherty,E Kevin Hall,Cecilia Di Pentima,Cecilia Di Pentima,Matthew E. Oster,Elijah Paintsil,Saira Siddiqui,Donna M. Timchak,Donna M. Timchak,Judith A. Guzman-Cottrill +21 more
TL;DR: In this paper, the authors report 7 cases of acute myocarditis or myopericarditis in healthy male adolescents who presented with chest pain all within 4 days after the second dose of Pfizer-BioNTech COVID-19 vaccination.
Journal ArticleDOI
Subtypes of Human Immunodeficiency Virus Type 1 and Disease Stage among Women in Nairobi, Kenya
Joel R. Neilson,Grace C. John,Jean K. Carr,Paul Lewis,Joan K. Kreiss,Stephanie Jackson,Ruth Nduati,Dorothy Mbori-Ngacha,Dana Panteleeff,Sharon Bodrug,Christina Giachetti,Martha A. Bott,Barbra A. Richardson,Job J. Bwayo,Jeckoniah O. Ndinya-Achola,Julie Overbaugh,Julie Overbaugh +16 more
TL;DR: The data suggest that women in Kenya who are infected with subtype C viruses are at more advanced stages of immunosuppression than women infected withSubtype A or D, and intersubtype recombinant viral genomes may be very common in Kenya and in other parts of Africa where there are multiple subtypes.