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Paul Monagle

Researcher at Royal Children's Hospital

Publications -  395
Citations -  14736

Paul Monagle is an academic researcher from Royal Children's Hospital. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 53, co-authored 363 publications receiving 12579 citations. Previous affiliations of Paul Monagle include Monash Medical Centre & Hamilton Health Sciences.

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Antithrombotic therapy in neonates and children: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

TL;DR: The evidence supporting most recommendations for antithrombotic therapy in neonates and children remains weak and Studies addressing appropriate drug target ranges and monitoring requirements are urgently required in addition to site- and clinical situation-specific thrombosis management strategies.
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Antithrombotic Therapy in Neonates and Children: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)

TL;DR: Within this chapter, the majority of recommendations are separate for neonates and children, reflecting the significant differences in epidemiology of thrombosis and safety and efficacy of therapy in these two populations.
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Outcome of pediatric thromboembolic disease: a report from the Canadian Childhood Thrombophilia Registry.

TL;DR: The significant mortality and morbidity found in this study supports the need for international multicenter randomized clinical trials to determine optimal prophylactic and therapeutic treatment for children with DVT/PE.
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Developmental haemostasis : Impact for clinical haemostasis laboratories

TL;DR: The results confirm the need for coagulation laboratories to develop age-related reference ranges specific to their own testing systems and confirm that accurate diagnosis and management of neonates and children with suspected bleeding or clotting disorders is not possible.
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Antithrombotic Therapy in Children

TL;DR: The following review summarizes the available information on commonly used antithrombotic agents in children, which include standard heparin, low molecular hepar in, oral anticoagulants, thrombolytic therapy, antiplatelet agents, antithromabin concentrates, and protein C concentrates.