介绍了Kirk—Othmer Encyclopedia of Chemical Technology（化工技术百科全书）（第五版）电子图书网络版数据库，并对该数据库使用方法和检索途径作出了说明，且结合实例简单地介绍了该数据库的检索方法。

Kirk-Othmer Encyclopedia of Chemical Technology数据库介绍及实例

Melanogenesis is a process to synthesize melanin, which is a primary responsible for the pigmentation of human skin, eye and hair. Although numerous enzymatic catalyzed and chemical reactions are involved in melanogenesis process, the enzymes such as tyrosinase and tyrosinase-related protein-1 (TRP-1) and TRP-2 played a major role in melanin synthesis. Specifically, tyrosinase is a key enzyme, which catalyzes a rate-limiting step of the melanin synthesis, and the downregulation of tyrosinase is the most prominent approach for the development of melanogenesis inhibitors. Therefore, numerous inhibitors that target tyrosinase have been developed in recent years. The review focuses on the recent discovery of tyrosinase inhibitors that are directly involved in the inhibition of tyrosinase catalytic activity and functionality from all sources, including laboratory synthetic methods, natural products, virtual screening and structure-based molecular docking studies.

Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors.

Two widely applied spectrophotometric assays based on aluminium complex formation used for determination of total flavonoid content in food or medicinal plant samples were examined for several compounds from different classes of flavonoid family. The method which involves the measurement at 410–430 nm after addition of AlCl3 solution is selective only for flavonols and flavones luteolin. The procedure in the presence of NaNO2 in alkaline medium seems to be specific for rutin, luteolin and catechins, but also phenolic acids exhibit considerable absorbance at 510 nm. Application of both procedures to natural samples gave different order in terms of their flavonoid content. Thus, the expression “total flavonoid” content is not adequate as the results of both methods are dependent on the structure of the individual flavonoids present.

/pdf/evaluation-of-aluminium-complexation-reaction-for-flavonoid-4zt5xu2ncw.pdf

Evaluation of Aluminium Complexation Reaction for Flavonoid Content Assay

Catalytic conversion of renewable biomass to “green” chemicals and fuel additives has been extensively investigated in the past few decades. Interests on two top platform intermediates for biofuel production, i.e. levulinic acid (LA) and 5-hydroxymethylfurfural (HMF), have increased significantly. These two chemicals are generally produced from biomass through acid hydrolysis. This review summarizes the discoveries of the most recent studies on acid-catalyzed hydrolysis, including (i) biomass pretreatment, (ii) glucose production from cellulose hydrolysis, (iii) fructose formation from glucose isomerization, (iv) HMF formation from glucose/fructose dehydration and (v) LA production from HMF rehydration. Humins, the main byproducts, are also discussed in the aspect of their influence on the hydrolysis process, structure, formation mechanism, and applications.

From lignocellulosic biomass to levulinic acid: A review on acid-catalyzed hydrolysis

Current perspective on pretreatment technologies using lignocellulosic biomass: An emerging biorefinery concept

Identification and quantification of phenolic compounds of selected fruits from Madeira Island by HPLC-DAD-ESI-MS(n) and screening for their antioxidant activity.

Fructo- and galacto-oligosaccharides (FOS and GOS) are non-digestible oligosaccharides with prebiotic properties that can be incorporated into a wide number of products. This review details the general outlines for the production of FOS and GOS, both by enzymatic synthesis using disaccharides or other substrates, and by hydrolysis of polysaccharides. Special emphasis is laid on technological aspects, raw materials, properties, and applications.

/pdf/technological-aspects-of-the-production-of-fructo-and-1y2ti6zlym.pdf

Technological Aspects of the Production of Fructo and Galacto-Oligosaccharides. Enzymatic Synthesis and Hydrolysis.

https://digituma.uma.pt/bitstream/10400.13/3234/1/Evaluation%20of%20the%20antimicrobial%20and%20antioxidant%20activities%20of%20essential%20oils%2c%20extracts%20and%20their%20main%20components%20from%20oregano%20from%20Madeira%20Island.pdf

Evaluation of the antimicrobial and antioxidant activities of essential oils, extracts and their main components from oregano from Madeira Island, Portugal

Antioxidant potential of Artemisia argentea L'Hér alcoholic extract and its relation with the phenolic composition

https://digituma.uma.pt/bitstream/10400.13/3256/1/Characterisation%20of%20phenolic%20acid%20derivatives%20and%20flavonoids%20from%20different.pdf

Characterisation of phenolic acid derivatives and flavonoids from different morphological parts of Helichrysum obconicum by a RP-HPLC–DAD-(−)–ESI-MSn method

Paula C. Castilho

Papers

Identification and quantification of phenolic compounds of selected fruits from Madeira Island by HPLC-DAD-ESI-MS(n) and screening for their antioxidant activity.

Technological Aspects of the Production of Fructo and Galacto-Oligosaccharides. Enzymatic Synthesis and Hydrolysis.

Evaluation of the antimicrobial and antioxidant activities of essential oils, extracts and their main components from oregano from Madeira Island, Portugal

Antioxidant potential of Artemisia argentea L'Hér alcoholic extract and its relation with the phenolic composition

Characterisation of phenolic acid derivatives and flavonoids from different morphological parts of Helichrysum obconicum by a RP-HPLC–DAD-(−)–ESI-MSn method