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Pauline Brice

Researcher at University of Paris

Publications -  243
Citations -  14207

Pauline Brice is an academic researcher from University of Paris. The author has contributed to research in topics: Brentuximab vedotin & Follicular lymphoma. The author has an hindex of 56, co-authored 227 publications receiving 12729 citations.

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High-dose therapy with autologous stem-cell transplantation (ASCT) after first progression prolonged survival of follicular lymphoma patients included in the prospective GELF 86 protocol

TL;DR: High-dose therapy with ASCT compared to standard treatment prolonged remission and survival after first progression of FL patients and Multivariate analysis of parameters significant according to univariate analysis found that no ASCT at first progression, age at relapse > 50 years, progression on-therapy were adversely significant on survival.
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ABVD (8 cycles) versus BEACOPP (4 escalated cycles ≥4 baseline): final results in stage III–IV low-risk Hodgkin lymphoma (IPS 0–2) of the LYSA H34 randomized trial

TL;DR: Fewer progressions/relapses were observed with BEACOPP, demonstrating the high efficacy of the more intensive regimen, even in low-risk patients, and additional considerations, balancing treatment-related toxicity and late morbidity due to salvage may help with decision-making with regard to treatment with ABVD.
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Low-Grade Stage III-IV Follicular Lymphoma: Multivariate Analysis of Prognostic Factors in 484 Patients—A Study of the Groupe d'Etude des Lymphomes de l'Adulte

TL;DR: The IPI was prognostic for OS, but in this population, a very low number of patients belonged to the high-risk groups, so three prognostic factors for poor OS were identified.
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Managing relapsed and refractory Hodgkin lymphoma.

TL;DR: Patients with relapsed HL should be identified according to their prognostic factors at relapse (duration of remission and extranodal disease or stage), and the role of tandem HDT or allogeneic SCT should be proposed for patients not in complete remission at the time of HDT.