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Pauline Byakika-Kibwika
Researcher at Trinity College, Dublin
Publications - 12
Citations - 470
Pauline Byakika-Kibwika is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Nevirapine & Cmax. The author has an hindex of 11, co-authored 12 publications receiving 428 citations. Previous affiliations of Pauline Byakika-Kibwika include Makerere University & College of Health Sciences, Bahrain.
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Journal ArticleDOI
Medicinal plants used by traditional medicine practitioners for the treatment of HIV/AIDS and related conditions in Uganda
Mohammed Lamorde,John R. S. Tabuti,Celestino Obua,Collins Kukunda-Byobona,Hindam Lanyero,Pauline Byakika-Kibwika,Pauline Byakika-Kibwika,Godfrey S. Bbosa,Aloysius Lubega,Jasper Ogwal-Okeng,Máirín Ryan,Paul Waako,Concepta Merry +12 more
TL;DR: In this article, the authors conducted a survey to document herbal medicines used in the treatment of HIV/AIDS and related opportunistic infections, and to document the existing knowledge, attitudes and practices related to HIV recognition, control and treatment in Sembabule, Kamuli, Kabale and Gulu districts in Uganda.
Journal ArticleDOI
Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adults.
Pauline Byakika-Kibwika,Pauline Byakika-Kibwika,Mohammed Lamorde,Mohammed Lamorde,Jonathan Mayito,Lillian Nabukeera,Rhoda Namakula,Harriet Mayanja-Kizza,Elly Katabira,Muhammad Ntale,Nadine Pakker,Máirín Ryan,Warunee Hanpithakpong,Joel Tarning,Joel Tarning,Niklas Lindegardh,Niklas Lindegardh,Peter J. de Vries,Saye Khoo,David Back,Concepta Merry,Concepta Merry +21 more
TL;DR: These drug interactions may increase the risk of malaria treatment failure and development of resistance to artemether/lumefantrine and nevirapine, and clinical data from population pharmacokinetic and pharmacodynamic trials evaluating the impact of these drug interactions are urgently needed.
Journal ArticleDOI
Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults
Pauline Byakika-Kibwika,Pauline Byakika-Kibwika,Mohammed Lamorde,Mohammed Lamorde,Violet Okaba-Kayom,Harriet Mayanja-Kizza,Elly Katabira,Warunee Hanpithakpong,Nadine Pakker,Thomas P. C. Dorlo,Joel Tarning,Joel Tarning,Niklas Lindegardh,Niklas Lindegardh,Peter J. de Vries,David Back,Saye Khoo,Concepta Merry,Concepta Merry +18 more
TL;DR: Co-administration of artemether/lumfantrine with lopinavir/ritonavir significantly increases lumefantrine exposure, but decreases artem ether exposure.
Journal ArticleDOI
Effect of Food on the Steady-State Pharmacokinetics of Tenofovir and Emtricitabine plus Efavirenz in Ugandan Adults
Mohammed Lamorde,Pauline Byakika-Kibwika,Pauline Byakika-Kibwika,William S. Tamale,Francis Kiweewa,Máirín Ryan,Alieu Amara,John Tjia,David Back,Saye Khoo,Marta Boffito,Cissy Kityo,Concepta Merry +12 more
TL;DR: The effect of food on the steady-state pharmacokinetics of a proprietary fixed-dose combination (FDC) tablet containing tenofovir disoproxil fumarate (TDF)/emtricitabine/efavirenz should be taken without food by patients experiencing central nervous system toxicities.
Journal ArticleDOI
The Effect of Gene Variants on Levonorgestrel Pharmacokinetics When Combined With Antiretroviral Therapy Containing Efavirenz or Nevirapine.
Megan Neary,Mohammed Lamorde,Adeniyi Olagunju,Kristin M. Darin,Concepta Merry,Pauline Byakika-Kibwika,David Back,Marco Siccardi,Andrew Owen,Kimberly K. Scarsi +9 more
TL;DR: Pharmacogenetic variations influenced subdermal levonorgestrel pharmacokinetics in HIV‐positive women, indicating that the magnitude of the interaction with non‐nucleoside reverse transcriptase inhibitors (NNRTIs) is influenced by host genetics.