W
Warunee Hanpithakpong
Researcher at Mahidol University
Publications - 42
Citations - 4645
Warunee Hanpithakpong is an academic researcher from Mahidol University. The author has contributed to research in topics: Dihydroartemisinin & Piperaquine. The author has an hindex of 22, co-authored 40 publications receiving 4207 citations. Previous affiliations of Warunee Hanpithakpong include University of Oxford.
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Journal ArticleDOI
Artemisinin Resistance in Plasmodium falciparum Malaria
Arjen M. Dondorp,François Nosten,Poravuth Yi,Debashish Das,Aung Phae Phyo,Joel Tarning,Khin Maung Lwin,Frédéric Ariey,Warunee Hanpithakpong,Sue J. Lee,Pascal Ringwald,Kamolrat Silamut,Mallika Imwong,Kesinee Chotivanich,Pharath Lim,Trent Herdman,Sen Sam An,Shunmay Yeung,Pratap Singhasivanon,Nicholas P. J. Day,Niklas Lindegardh,Duong Socheat,Nicholas J. White +22 more
TL;DR: The overall median clearance times were 84 hours (interquartile range, 60 to 96) in Pailin and 48 hours in Wang Pha (P<0.001) in each of the two locations as discussed by the authors.
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Declining Responsiveness of Plasmodium falciparum Infections to Artemisinin-Based Combination Treatments on the Kenyan Coast
Steffen Borrmann,Steffen Borrmann,Philip Sasi,Philip Sasi,Leah Mwai,Mahfudh Bashraheil,Ahmed M Abdallah,Steven Muriithi,Henrike Frühauf,Henrike Frühauf,Barbara Schaub,Barbara Schaub,Johannes Pfeil,Johannes Pfeil,Judy Peshu,Warunee Hanpithakpong,Anja Rippert,Elizabeth Juma,Benjamin Tsofa,Moses Mosobo,Brett Lowe,Faith H. A. Osier,Greg Fegan,Niklas Lindegardh,Alexis Nzila,Norbert Peshu,Margaret J. Mackinnon,Margaret J. Mackinnon,Kevin Marsh,Kevin Marsh +29 more
TL;DR: The significant, albeit small, decline through time of parasitological response rates to treatment with ACTs may be due to the emergence of parasites with reduced drug sensitivity, to the coincident reduction in population-level clinical immunity, or both.
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Pharmacokinetics of High-Dose Oseltamivir in Healthy Volunteers
Yupaporn Wattanagoon,Kasia Stepniewska,Kasia Stepniewska,Niklas Lindegardh,Niklas Lindegardh,Sasithon Pukrittayakamee,Udomsak Silachamroon,Watcharapong Piyaphanee,T Singtoroj,Warunee Hanpithakpong,Geraint Davies,Joel Tarning,Wirichada Pongtavornpinyo,C. Fukuda,Pratap Singhasivanon,Nicholas P. J. Day,Nicholas P. J. Day,Nicholas J. White,Nicholas J. White +18 more
TL;DR: Probenecid coadministration may allow considerable dose saving for oseltamivir, but more information on OC penetration into respiratory secretions is needed to devise appropriate dose regimens.
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Population Pharmacokinetics and Pharmacodynamics of Piperaquine in Children With Uncomplicated Falciparum Malaria
Joel Tarning,Joel Tarning,Issaka Zongo,Fabrice A. Somé,Noel Rouamba,Sunil Parikh,Philip J. Rosenthal,Warunee Hanpithakpong,N Jongrak,Nicholas P. J. Day,Nicholas P. J. Day,Nicholas J. White,Nicholas J. White,François Nosten,J-B Ouedraogo,Niklas Lindegardh,Niklas Lindegardh +16 more
TL;DR: The individually predicted day 7 capillary plasma concentration of piperaquine was an important predictor (P < 0.0001) of recurrent malaria infection after treatment and an increased dose regimen for young children should be evaluated.
Journal ArticleDOI
Population Pharmacokinetics of Dihydroartemisinin and Piperaquine in Pregnant and Nonpregnant Women with Uncomplicated Malaria
Joel Tarning,Joel Tarning,Marcus J. Rijken,Rose McGready,Rose McGready,Aung Pyae Phyo,Warunee Hanpithakpong,Nicholas P. J. Day,Nicholas P. J. Day,Nicholas J. White,Nicholas J. White,François Nosten,François Nosten,Niklas Lindegardh,Niklas Lindegardh +14 more
TL;DR: The main pharmacokinetic finding was an unaltered total exposure to piperaquine but reduced exposure to dihydroartemisinin in pregnant compared to nonpregnant women with uncomplicated malaria.