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Pauline M. Doran
Researcher at Swinburne University of Technology
Publications - 94
Citations - 5709
Pauline M. Doran is an academic researcher from Swinburne University of Technology. The author has contributed to research in topics: Tissue engineering & Cartilage. The author has an hindex of 40, co-authored 94 publications receiving 5421 citations. Previous affiliations of Pauline M. Doran include Monash University & California Institute of Technology.
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Growth kinetics and stoichiometry of Mentha citrata shooty teratomas transformed by Agrobacterium tumefaciens
TL;DR: Based on calculated kinetic and yield parameters, a stoichiometric equation was developed to describe growth in media containing both nitrate and ammonia, which showed that delivery of adequate oxygen to completely submerged shoots depends on the elimination of hydrodynamic boundary layers at high external liquid velocity.
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Production of zebrafish cardiospheres and cardiac progenitor cells in vitro and three‐dimensional culture of adult zebrafish cardiac tissue in scaffolds
TL;DR: Three-dimensional culture of zebrafish heart cells in fibrous polyglycolic acid (PGA) scaffolds was carried out under dynamic fluid flow conditions, expanding the technical capabilities for three-dimensional zebra fish cardiac cell culture with potential applications in tissue engineering, drug and toxicology screening, and ontogeny research.
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Electrical stimulation of cell growth and neurogenesis using conductive and nonconductive microfibrous scaffolds.
TL;DR: It is demonstrated that substantial benefits in terms of cell growth and neural differentiation can be obtained using electric fields exerted across nonconductive microfibrous scaffolds, and that this approach to electrical stimulation can be more effective than when the stimulus is applied to cells on conductive scaffolds.
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Stimulation of cell growth and neurogenesis using protein-functionalized microfibrous scaffolds and fluid flow in bioreactors
TL;DR: This work demonstrates the significant beneficial effects of features of the physical culture environment, such as hydrodynamic conditions and cell attachment surface geometry, in regulating culture performance.
Proceedings ArticleDOI
Microfluidic chip containing porous gradient for chemotaxis study
TL;DR: The chemotactic responses of cancer cells were successfully monitored, the validity of using in situ porous hydrogels as a construction material for a microchemotaxis device was confirmed, and the potential of the hydrogel with tunable porosity based microfluidic device was demonstrated in biological experiments.