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Pauline M. Doran
Researcher at Swinburne University of Technology
Publications - 94
Citations - 5709
Pauline M. Doran is an academic researcher from Swinburne University of Technology. The author has contributed to research in topics: Tissue engineering & Cartilage. The author has an hindex of 40, co-authored 94 publications receiving 5421 citations. Previous affiliations of Pauline M. Doran include Monash University & California Institute of Technology.
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Journal ArticleDOI
Design of Mixing Systems for Plant Cell Suspensions in Stirred Reactors
TL;DR: An engineering analysis is used to identify which agitators and operating regimes have greatest potential for high‐density plant culture applications, irrespective of whether they have been tested experimentally.
Journal ArticleDOI
"Race for the Surface": Eukaryotic Cells Can Win.
Vy T. H. Pham,Vi Khanh Truong,Anna Orlowska,Shahram Ghanaati,Mike Barbeck,Patrick Booms,Alex J. Fulcher,Chris M. Bhadra,R. Buividas,Vladimir Baulin Baulin,C. James Kirkpatrick,Pauline M. Doran,David E. Mainwaring,Saulius Juodkazis,Russell J. Crawford,Russell J. Crawford,Elena P. Ivanova +16 more
TL;DR: It is demonstrated for the first time that a precise nanotopology provides an effective intervention in bacterial cocolonization enabling the proliferation of eukaryotic cells on a substratum surface, preinfected by both live Gram-negative, Pseudomonas aeruginosa, and Gram-positive, Staphylococcus aureus, pathogenic bacteria.
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Tissue engineering of human cartilage and osteochondral composites using recirculation bioreactors.
TL;DR: The beneficial effects of generating cartilage tissues in contact with developing bone and the feasibility of producing composite osteochondral constructs for clinical application using recirculation column bioreactors are demonstrated.
Journal ArticleDOI
Characteristics of growth and tropane alkaloid synthesis in Atropa belladonna roots transformed by Agrobacterium rhizogenes
Janet M. Sharp,Pauline M. Doran +1 more
TL;DR: Growth of Atropa belladonna hairy roots in shake flasks followed first-order kinetics, and levels of atropine in reactor-grown roots were higher than in shake-flask roots, and growth and substrate conversion were better inshake flasks.
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Tissue engineering of human cartilage in bioreactors using single and composite cell‐seeded scaffolds
TL;DR: It is demonstrated that the location of regions of high cell density in the scaffold coupled with application of dynamic bioreactor operating conditions has a significant influence on the quality of tissue-engineered cartilage.