P
Pavla Bojarová
Researcher at Academy of Sciences of the Czech Republic
Publications - 83
Citations - 1924
Pavla Bojarová is an academic researcher from Academy of Sciences of the Czech Republic. The author has contributed to research in topics: Chemistry & Glycosylation. The author has an hindex of 23, co-authored 67 publications receiving 1529 citations. Previous affiliations of Pavla Bojarová include Schiller International University & University of Melbourne.
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Journal ArticleDOI
Selectively Deoxyfluorinated N-Acetyllactosamine Analogues as 19F NMR Probes to Study Carbohydrate-Galectin Interactions.
Martin Kurfiřt,Martin Kurfiřt,Martin Dračínský,Lucie Červenková Šťastná,Petra Cuřínová,Vojtěch Hamala,Vojtěch Hamala,Michaela Hovorková,Pavla Bojarová,Jindřich Karban +9 more
TL;DR: In this article, a complete series of six mono-deoxyfluorinated analogues of N-Acetyllactosamine (Galβ1-4GlcNAc, LacNAc) was synthesized, in which each hydroxyl has been selectively replaced by fluorine while the anomeric position has been protected as methyl β-glycoside.
OtherDOI
Glycosidases in synthesis
TL;DR: In recent decades, there has been a boom in carbohydrate chemistry, evoked by the increasing need for new carbohydrate materials and by the dynamic development of glycomics as mentioned in this paper, however, the tedious protection, activation, and dep...
Journal ArticleDOI
Recent trends in the treatment of cyanide-containing effluents: Comparison of different approaches
TL;DR: A review of recent advances in this research area can be found in this paper , where a general overview of innovative methods of different types (oxidation, flocculation, adsorption, electro(dia)lysis, photocatalysis, bioassimilation, biocatalysis).
Journal ArticleDOI
Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short
Pavla Bojarová,Vladimir Kren +1 more
TL;DR: In this paper, two approaches to glycosidase catalysis are presented: (i) the use of structurally modified substrates that carry various functional moieties in the molecule, and (ii) the design of mutant glyco-sidases void of hydrolytic activity.
Journal ArticleDOI
Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars.
Valeria Pingitore,Macarena Martínez-Bailén,Ana T. Carmona,Zuzana Mészáros,Natalia Carolina Peralta Kulik,Kristýna Slámová,Vladimir Kren,Pavla Bojarová,Inmaculada Robina,Antonio J. Moreno-Vargas +9 more
TL;DR: In this article , two libraries of mono-and dimeric pyrrolidine iminosugars were synthesized by CuAAC and (thio)urea-bond-forming reactions from the respective azido/aminohexylpyrrolidine iminosugar precursors.