P
Pedro Fernández-Llebrez
Researcher at University of Málaga
Publications - 95
Citations - 3066
Pedro Fernández-Llebrez is an academic researcher from University of Málaga. The author has contributed to research in topics: Subcommissural organ & Ependyma. The author has an hindex of 29, co-authored 95 publications receiving 2725 citations.
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Journal ArticleDOI
Microglia Morphological Categorization in a Rat Model of Neuroinflammation by Hierarchical Cluster and Principal Components Analysis.
María del Mar Fernández-Arjona,Jesús M. Grondona,Pablo Granados-Durán,Pedro Fernández-Llebrez,M. D. López-Avalos +4 more
TL;DR: Microglia undergo a quantifiable morphological change upon neuraminidase induced inflammation and an objective method for microglia classification based on morphological parameters is proposed.
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Skeletal deformities in larval, juvenile and adult stages of cultured gilthead sea bream (Sparus aurata L.)
TL;DR: Skeletal deformities in larval, juvenile and adult stages of fish from a Spanish experimental culturing centre are studied, characterised by V-shaped dorsoventral curvature of the body axis including the vertebral column and the spinal cord.
Journal ArticleDOI
Structure and function of the ependymal barrier and diseases associated with ependyma disruption
Antonio J. Jiménez,María-Dolores Domínguez-Pinos,Maria Montserrat Guerra,Pedro Fernández-Llebrez,J. M. Pérez-Fígares +4 more
TL;DR: The neuroepithelium is a germinal epithelium containing progenitor cells that produce almost all of the central nervous system cells, including the ependyma; therefore, they separate the cerebrospinal fluid that fills cavities from the developing or mature brain parenchyma.
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IGF‐I stimulates neurogenesis in the hypothalamus of adult rats
Margarita Pérez-Martín,Manuel Cifuentes,Jesús M. Grondona,M. D. López-Avalos,Ulises Gómez-Pinedo,José Manuel García-Verdugo,Pedro Fernández-Llebrez +6 more
TL;DR: After intracerebroventricular treatment with insulin‐like growth factor I (IGF‐I), cell proliferation significantly increased in both the periventricular and the parenchymal zones of the whole hypothalamus, suggesting that the central overlapping zone of the rat hypothalamic wall could be considered a neurogenic niche in response to IGF‐I.
Journal ArticleDOI
Absence of LPA1 Signaling Results in Defective Cortical Development
Guillermo Estivill-Torrús,Pedro Llebrez-Zayas,Elisa Matas-Rico,Luis J. Santín,Carmen Pedraza,Isabel de Diego,Ignacio del Arco,Pedro Fernández-Llebrez,Jerold Chun,Fernando Rodríguez de Fonseca +9 more
TL;DR: A role for LPA(1) in cortical neural precursors resulting from analysis of a variant of a previously characterized LPA-null mutant that arose spontaneously during colony expansion is reported and it is suggested that the presence of genetic modifiers of LPA (1) influences cerebral cortical development.