U
Ulises Gómez-Pinedo
Researcher at Complutense University of Madrid
Publications - 111
Citations - 3309
Ulises Gómez-Pinedo is an academic researcher from Complutense University of Madrid. The author has contributed to research in topics: Subventricular zone & Neurogenesis. The author has an hindex of 26, co-authored 98 publications receiving 2601 citations. Previous affiliations of Ulises Gómez-Pinedo include Consejo Nacional de Ciencia y Tecnología & University of Valencia.
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Journal ArticleDOI
Hyperammonemia Induces Neuroinflammation That Contributes to Cognitive Impairment in Rats With Hepatic Encephalopathy
Regina Rodrigo,Omar Cauli,Ulises Gómez-Pinedo,Ana Agusti,Vicente Hernandez-Rabaza,José Manuel García-Verdugo,Vicente Felipo +6 more
TL;DR: Chronic hyperammonemia is sufficient to induce microglial activation and neuroinflammation; these contribute to the cognitive and motor alterations that occur during hepatic encephalopathy.
Journal ArticleDOI
Neuronal Activity Drives Localized Blood-Brain-Barrier Transport of Serum Insulin-like Growth Factor-I into the CNS
Takeshi Nishijima,Joaquin Piriz,Sylvie Duflot,Ana M. Fernandez,Gema Gaitan,Ulises Gómez-Pinedo,José Manuel García Verdugo,Felix Leroy,Hideaki Soya,Angel Nuñez,Ignacio Torres-Aleman +10 more
TL;DR: Activity-dependent entrance of serum IGF-I into the CNS may help to explain disparate observations such as proneurogenic effects of epilepsy, rehabilitatory effects of neural stimulation, and modulatory effects of blood flow on brain activity.
Journal ArticleDOI
Proliferation in the human ipsilateral subventricular zone after ischemic stroke
Joan Martí-Fàbregas,Miriam Romaguera-Ros,Ulises Gómez-Pinedo,Sergi Martinez-Ramirez,Elena Jiménez-Xarrié,Rebeca Marín,Josep-Lluis Martí-Vilalta,José Manuel García-Verdugo +7 more
TL;DR: Examination of coronal brain slices from patients who died after a first-ever cerebral nonlacunar infarction in the middle cerebral artery territory found unequivocal evidence of active cell proliferation in the ipsilateral subventricular zone following an acute ischemic stroke in patients.
Journal ArticleDOI
IGF‐I stimulates neurogenesis in the hypothalamus of adult rats
Margarita Pérez-Martín,Manuel Cifuentes,Jesús M. Grondona,M. D. López-Avalos,Ulises Gómez-Pinedo,José Manuel García-Verdugo,Pedro Fernández-Llebrez +6 more
TL;DR: After intracerebroventricular treatment with insulin‐like growth factor I (IGF‐I), cell proliferation significantly increased in both the periventricular and the parenchymal zones of the whole hypothalamus, suggesting that the central overlapping zone of the rat hypothalamic wall could be considered a neurogenic niche in response to IGF‐I.
Journal ArticleDOI
Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and spatial reversal.
Vicente Hernandez-Rabaza,María Llorens-Martín,Clara Velázquez-Sánchez,Antonio Ferragud,A. Arcusa,H.G. Gumus,Ulises Gómez-Pinedo,Ana Perez-Villalba,Joan V. Roselló,José Luis Trejo,Juan A. Barcia,Juan J. Canales +11 more
TL;DR: Data demonstrate that reduced adult hippocampal neurogenesis produces marked deficits in the rapid acquisition of emotionally relevant contextual information but spares spatial working memory function, the long-term retention of acquired spatial rules and the ability to flexibly modify learned spatial strategies.