P
Pedro Madureira
Researcher at University of Porto
Publications - 51
Citations - 1544
Pedro Madureira is an academic researcher from University of Porto. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 18, co-authored 37 publications receiving 1256 citations. Previous affiliations of Pedro Madureira include Institute of Business & Medical Careers & Instituto de Biologia Molecular e Celular.
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Journal ArticleDOI
Structure–function relationships of immunostimulatory polysaccharides: A review
TL;DR: This review introduces basic immunological concepts required to understand the mechanisms that rule the potential claimed immunostimulatory activity of polysaccharides and critically presents a literature survey on the structural features of the poly Saccharide and reported immunostIMulatory activity.
Journal ArticleDOI
Group B streptococcus GAPDH is released upon cell lysis, associates with bacterial surface, and induces apoptosis in murine macrophages.
Liliana Oliveira,Pedro Madureira,Pedro Madureira,Elva Bonifácio Andrade,Elva Bonifácio Andrade,Abdelouhab Bouaboud,Abdelouhab Bouaboud,Eric Morello,Paula Ferreira,Paula Ferreira,Claire Poyart,Claire Poyart,Patrick Trieu-Cuot,Shaynoor Dramsi +13 more
TL;DR: It is found that impaired GAPDH presence in the surface and supernatant of GBS was associated with a lower level of bacterial lysis, and a novel function of the secreted GAPDh as an inducer of apoptosis of murine macrophages is provided.
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The influence of functional groups of self-assembled monolayers on fibrous capsule formation and cell recruitment
TL;DR: The data indicate that implant surfaces coated with CH( 3) induce thick fibrous capsules and this may be the result of the stronger inflammatory effect of CH(3) in comparison with COOH or OH chemical groups.
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Protection against systemic candidiasis in mice immunized with secreted aspartic proteinase 2.
Manuel Vilanova,Luzia Teixeira,Íris Caramalho,Egídio Torrado,Andreia Marques,Pedro Madureira,Adília Ribeiro,Paula Ferreira,Miguel Gama,Jocelyne Demengeot +9 more
TL;DR: It is demonstrated that Sap2 can be successfully used as a vaccination target in systemic candidiasis and reveals the potential immunomodulatory role of Sap2 on C. albicans infection.
Journal ArticleDOI
Purification, structure and immunobiological activity of an arabinan-rich pectic polysaccharide from the cell walls of Prunus dulcis seeds.
Fernando Dourado,Pedro Madureira,Vera Carvalho,Ricardo Coelho,Manuel A. Coimbra,Manuel Vilanova,Manuel Mota,Francisco M. Gama +7 more
TL;DR: The crude polysaccharide extract and fractions A and E induced a murine lymphocyte stimulatory effect, as evaluated by the in vitro and in vivo expression of lymphocyte activation markers and spleen mononuclear cells culture proliferation.