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Penelope A. Morel
Researcher at University of Pittsburgh
Publications - 102
Citations - 6597
Penelope A. Morel is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: T cell & Antigen. The author has an hindex of 41, co-authored 99 publications receiving 6203 citations. Previous affiliations of Penelope A. Morel include Stanford University.
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In vivo imaging platform for tracking immunotherapeutic cells
TL;DR: A magnetic resonance imaging technology that uses perfluoropolyether (PFPE) agents to track cells in vivo and labels phenotypically defined dendritic cells (DCs) with PFPE ex vivo is presented.
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Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study.
TL;DR: The results demonstrated that haplotypes carrying an aspartic acid in position 57 (Asp-57) of their DQ beta chain were significantly increased in frequency among nondiabetic haplotypes, while non-AsP-57 haplotypes were significantly increase in frequencyamong diabetic haplotypes.
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Dendritic cells mediate NK cell help for Th1 and CTL responses: two-signal requirement for the induction of NK cell helper function.
Robbie B. Mailliard,Young Ik Son,Richard E. Redlinger,Patrick T. Coates,Adam Giermasz,Penelope A. Morel,Walter J. Storkus,Pawel Kalinski +7 more
TL;DR: It is reported that NK cells are capable of inducing stable type 1-polarized “effector/memory” DC (DC1) that act as carriers of NK cell-derived helper signals for the development of type 1 immune responses.
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Fluorine-19 MRI for visualization and quantification of cell migration in a diabetes model.
TL;DR: The in vivo quantification and cell trafficking patterns were verified using 19F spectroscopy and fluorescence microscopy in excised pancreata and the labeling procedure did not affect T‐cell migration in vivo.
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Crossregulation between Th1 and Th2 cells.
TL;DR: The crossregulation between Th1 and Th2 cells is summarized in terms of the changes in cytokine receptor expression and function that occur during differentiation.