Penny A. Williams

TL;DR: It is concluded that prolonged ganciclovir prophylaxis decreases the early incidence of CMV and OB among lung transplant recipients, but these effects are of finite duration.

TL;DR: It is concluded that CMV pulmonary infections among LTX result in serious late sequelae and that current treatment is ineffectual for prevention of viral-associated CR in these patients.

TL;DR: It is demonstrated that the tumor lesions exhibit varying patterns of restricted viral gene expression, and LCL derived from these lesions may represent the in vitro selection of cell subpopulations; and immunosuppressed individuals have a markedly reduced antibody response to the latent cycle antigens, EBNA1,EBNA2, and EBNA-LP, but not to the lytic cycle viral capsid antigen when compared with normal immunocompetent controls.

TL;DR: The occurrence of this rapidly fatal ADV pneumonia mainly affecting the pediatric population, early in the posttransplantation course, suggests that the infection is primary to the recipient with ADV either originating and reactivating in the donor lung or acquired from the upper respiratory tract of the recipient.

TL;DR: Unsuspected rejection and/or infection that required therapy in 25% (90/355) of all surveillance bronchoscopy procedures were found.