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Pertti Lipponen
Researcher at University of Eastern Finland
Publications - 188
Citations - 7860
Pertti Lipponen is an academic researcher from University of Eastern Finland. The author has contributed to research in topics: Mitotic index & Breast cancer. The author has an hindex of 48, co-authored 188 publications receiving 7673 citations. Previous affiliations of Pertti Lipponen include University of Turku.
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Prognostic value of tumour‐infiltrating lymphocytes (TILs) in colorectal cancer
TL;DR: Clinical follow‐up data of 276 colorectal adenocarcinoma patients treated in Kuopio University Hospital between 1976 and 1986 and followed up for a mean of 14 years were analysed, finding that tumour‐infiltrating lymphocytes (TILs) were an independent prognostic factor of survival in all cases and independently predicted recurrence‐free survival.
Journal Article
Tumor Cell-associated Hyaluronan as an Unfavorable Prognostic Factor in Colorectal Cancer
K M Ropponen,Markku Tammi,Jyrki Parkkinen,Matti Eskelinen,Raija Tammi,Pertti Lipponen,Ulla M. Ågren,Esko Alhava,Veli-Matti Kosma +8 more
TL;DR: It is concluded that a high proportion of HA-positive cancer cells and high intensity of the HA-signal predicts a poor survival rate and the abnormal expression of HA in the neoplastic colon epithelial cells is suggested to provide a distinct advantage for invasive growth and metastasis.
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Lymphocyte infiltrates as a prognostic variable in female breast cancer
Sirpa Aaltomaa,Pertti Lipponen,Matti Eskelinen,Veli-Matti Kosma,S. Marin,Esko Alhava,Kari Syrjänen +6 more
TL;DR: The results clearly confirm the presence of efficient immunological antitumour defence mechanisms in human breast cancer and tumour-host interactions are subject to further studies particularly in axillary lymph-node negative breast cancer.
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Histological grade, perineural infiltration, tumour-infiltrating lymphocytes and apoptosis as determinants of long-term prognosis in prostatic adenocarcinoma
TL;DR: The results suggest that the Gleason score, PNI and the density of TIL should be included in routine pathology reports, to be used by clinicians while making therapeutic decisions in prostatic cancer.
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Over‐expression of p53 nuclear oncoprotein in transitional‐cell bladder cancer and its prognostic value
TL;DR: It is confirmed that p53 is involved in the growth regulation of bladder cancer and is certainly a subject for detailed analysis of specific mutations.