P
Peter C. Konturek
Researcher at University of Jena
Publications - 180
Citations - 5983
Peter C. Konturek is an academic researcher from University of Jena. The author has contributed to research in topics: Helicobacter pylori & Gastric mucosa. The author has an hindex of 42, co-authored 175 publications receiving 5374 citations. Previous affiliations of Peter C. Konturek include University of Erlangen-Nuremberg.
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Journal ArticleDOI
Continuous Positive Airway Pressure Treatment Rapidly Improves Insulin Sensitivity in Patients with Obstructive Sleep Apnea Syndrome
Igor Alexander Harsch,Simin Pour Schahin,Martin Radespiel-Tröger,Oliver Weintz,Holger Jahreiss,Florian S. Fuchs,Gunther H. Wiest,Eckhart G. Hahn,Tobias Lohmann,Peter C. Konturek,Joachim H. Ficker +10 more
TL;DR: The improved insulin sensitivity after 2 nights of treatment may reflect a decreasing sympathetic activity, indicating that sleep apnea is an independent risk factor for increased insulin resistance.
Journal Article
Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options
TL;DR: In this paper, the authors defined stress as an acute threat to homeostasis, and showed both short and long-term effects on the functions of the gastrointestinal tract, which can lead to the development of a broad array of gastrointestinal disorders including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and other functional gastrointestinal diseases, food antigen-related adverse responses, peptic ulcer and gastroesophageal reflux disease (GERD).
Journal Article
Gut clock: implication of circadian rhythms in the gastrointestinal tract
TL;DR: Identification of the molecular basis and role of melatonin in the regulation of circadian rhythm allows researchers and clinicians to approach gastrointestinal diseases from a chronobiological perspective.
Journal ArticleDOI
The Effect of Continuous Positive Airway Pressure Treatment on Insulin Sensitivity in Patients with Obstructive Sleep Apnoea Syndrome and Type 2 Diabetes
Igor Alexander Harsch,Simin Pour Schahin,Kerstin Brückner,Martin Radespiel-Tröger,Florian S. Fuchs,Eckhart G. Hahn,Peter C. Konturek,Tobias Lohmann,Joachim H. Ficker +8 more
TL;DR: The results indicate that OSA itself is an independent risk factor for insulin resistance, and this effect may be explained by the elevated sympathetic activity in OSA.
Journal ArticleDOI
Antrum- and corpus mucosa-infiltrating CD4(+) lymphocytes in Helicobacter pylori gastritis display a Th1 phenotype.
Frank Sommer,Gerhard Faller,Peter C. Konturek,Thomas Kirchner,Eckhart G. Hahn,Jürgen Zeus,Martin Röllinghoff,Michael Lohoff +7 more
TL;DR: CD4+ cells infiltrating antrum and corpus stomach mucosa during H. pylori infection show a Th1 phenotype, and this polarized Th1-type response may contribute to the inability of the immune system to eradicate the bacterium.