P
Peter D. Bevan
Researcher at University of Toronto
Publications - 19
Citations - 726
Peter D. Bevan is an academic researcher from University of Toronto. The author has contributed to research in topics: Microbubbles & Sonoporation. The author has an hindex of 12, co-authored 19 publications receiving 686 citations. Previous affiliations of Peter D. Bevan include Sunnybrook Health Sciences Centre & Ontario Institute for Cancer Research.
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Journal ArticleDOI
Sonoporation by ultrasound-activated microbubble contrast agents: effect of acoustic exposure parameters on cell membrane permeability and cell viability
TL;DR: The results indicate that ultrasound exposure parameters can be optimized for therapeutic sonoporation and that bubble disruption is a necessary but insufficient indicator of ultrasound-induced permeabilization.
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Microbubble mediated sonoporation of cells in suspension: clonogenic viability and influence of molecular size on uptake.
TL;DR: This study demonstrates that large macromolecules, up to 2 MDa in size, can be delivered with high efficiency to cells which undergo reversible permeabilisation, maintaining long-term viability in approximately half of the cells.
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Investigating perfluorohexane particles with high-frequency ultrasound.
TL;DR: Results confirm that liquid perfluorocarbon droplets behave as linear Rayleigh scatterers.
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B-scan ultrasound imaging of thermal coagulation in bovine liver: frequency shift attenuation mapping
TL;DR: B-scan attenuation mapping techniques are shown to be effective at differentiating and localizing the attenuation change associated with tissue coagulation, but that, in the analysis of phantom or ex vivo bovine liver data, electronic noise severely limits the effectiveness of these techniques.
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In vitro characterization of the subharmonic ultrasound signal from Definity microbubbles at high frequencies.
K. Cheung,Olivier Couture,Peter D. Bevan,Emmanuel Cherin,Ross Williams,Peter N. Burns,F.S. Foster +6 more
TL;DR: Numerical simulations of the Keller-Miksis model for the behavior of a single bubble and experimental investigations of Definity microbubbles in water supported the hypothesis that off-resonant bubbles, excited at their second harmonic, may be primarily responsible for the observed subharmonic energy.