P
Peter F. Whitington
Researcher at Children's Memorial Hospital
Publications - 271
Citations - 17236
Peter F. Whitington is an academic researcher from Children's Memorial Hospital. The author has contributed to research in topics: Liver transplantation & Transplantation. The author has an hindex of 72, co-authored 271 publications receiving 16201 citations. Previous affiliations of Peter F. Whitington include University of California, San Francisco & University of Rochester.
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Journal ArticleDOI
Liver transplantation in children from living related donors. Surgical techniques and results.
Christoph E. Broelsch,Peter F. Whitington,Jean C. Emond,Thomas G. Heffron,J. Richard Thistlethwaite,Larry Stevens,Piper Jb,Susan H. Whitington,J. Lance Lichtor +8 more
TL;DR: The left lateral segmentectomy presents minimal surgical trauma to the liver and should remain the primary approach for obtaining a liver graft from a living donor, and the acceptance of LRT for general clinical application in the authors' institution is led.
Journal ArticleDOI
Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.
Lalitha Iyer,Christopher D. King,Peter F. Whitington,Mitchell D. Green,S K Roy,Thomas R. Tephly,Birgit L. Coffman,Mark J. Ratain +7 more
TL;DR: Findings indicate a genetic predisposition to the metabolism of irinotecan, suggesting that patients with low UGT1A1 activity, such as those with Gilbert's syndrome, may be at an increased risk for irinOTecan toxicity.
Journal ArticleDOI
Application of reduced-size liver transplants as split grafts, auxiliary orthotopic grafts, and living related segmental transplants.
C. E. Broelsch,Jean C. Emond,Peter F. Whitington,J R Thistlethwaite,Alfred L. Baker,J. L. Lichtor +5 more
TL;DR: Overall the various modalities of using graft reduction have resulted in postoperative results similar to those achieved with full-size grafts, while pretransplantation mortality has been limited to less than 2%.
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Guideline for the evaluation of cholestatic jaundice in infants: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition.
Virginia Moyer,Deborah K. Freese,Peter F. Whitington,Alan D. Olson,Fred Brewer,Richard B. Colletti,Melvin B. Heyman +6 more
TL;DR: This document represents the official recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition on the evaluation of cholestatic jaundice in infants and is not intended as a substitute for clinical judgment or for the care of all patients with this problem.
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A multicenter study of the outcome of biliary atresia in the United States, 1997 to 2000.
Benjamin L. Shneider,Morton B. Brown,Barbara Haber,Peter F. Whitington,Kathleen B. Schwarz,Robert H. Squires,Jorge A. Bezerra,Ross W. Shepherd,Philip J. Rosenthal,Jay H. Hoofnagle,Ronald J. Sokol +10 more
TL;DR: Efforts to improve bile flow after HPE may lead to improved outcome in children with biliary atresia, and total bilirubin in early follow-up after HPe was highly predictive of outcome.