P
Peter J.C. Clarke
Researcher at University of Hertfordshire
Publications - 4
Citations - 2087
Peter J.C. Clarke is an academic researcher from University of Hertfordshire. The author has contributed to research in topics: Gene & Regulation of gene expression. The author has an hindex of 4, co-authored 4 publications receiving 1995 citations. Previous affiliations of Peter J.C. Clarke include California Institute of Technology.
Papers
More filters
Journal ArticleDOI
A Genomic Regulatory Network for Development
Eric H. Davidson,Jonathan P. Rast,Paola Oliveri,Andrew Ransick,Cristina Calestani,Chiou-Hwa Yuh,Takuya Minokawa,Gabriele Amore,Veronica F. Hinman,Cesar Arenas-Mena,Ochan Otim,C. Titus Brown,Carolina B. Livi,Pei Yun Lee,Roger Revilla,Alistair G. Rust,Zheng Jun Pan,Maria J. Schilstra,Peter J.C. Clarke,Maria Ina Arnone,Lee Rowen,R. Andrew Cameron,David R. McClay,Leroy Hood,Hamid Bolouri +24 more
TL;DR: A gene regulatory network that controls the specification of endoderm and mesoderm in the sea urchin embryo is summarized here and reveals specific and general aspects of development, such as how given cells generate their ordained fates in the embryo and why the process moves inexorably forward in developmental time.
Journal ArticleDOI
A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo.
Eric H. Davidson,Jonathan P. Rast,Paola Oliveri,Andrew Ransick,Cristina Calestani,Chiou-Hwa Yuh,Takuya Minokawa,Gabriele Amore,Veronica F. Hinman,Cesar Arenas-Mena,Ochan Otim,C. Titus Brown,Carolina B. Livi,Pei Yun Lee,Roger Revilla,Maria J. Schilstra,Peter J.C. Clarke,Alistair G. Rust,Zhengjun Pan,Maria Ina Arnone,Lee Rowen,R. Andrew Cameron,David R. McClay,Leroy Hood,Hamid Bolouri +24 more
TL;DR: The current form of a provisional DNA sequence-based regulatory gene network that explains in outline how endomesodermal specification in the sea urchin embryo is controlled is presented.
Journal ArticleDOI
New computational approaches for analysis of cis-regulatory networks.
C. Titus Brown,Alistair G. Rust,Peter J.C. Clarke,Zhengjun Pan,Maria J. Schilstra,Tristan De Buysscher,Gareth Griffin,Barbara J. Wold,R. Andrew Cameron,Eric H. Davidson,Hamid Bolouri +10 more
TL;DR: Several locally developed software tools that have been used in support of the embryogenesis of the sea urchin are presented and an overview of the process used to build the model of the Strongylocentrotus purpuratus endomesoderm gene network is presented.
Journal ArticleDOI
Patchy interspecific sequence similarities efficiently identify positive cis-regulatory elements in the sea urchin.
TL;DR: It is demonstrated that interspecific sequence conservation can provide a systematic guide to the identification of functional cis-regulatory elements within a large expanse of genomic DNA.