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Peter J. Hylands
Researcher at King's College London
Publications - 64
Citations - 3256
Peter J. Hylands is an academic researcher from King's College London. The author has contributed to research in topics: Baicalein & Cancer. The author has an hindex of 27, co-authored 63 publications receiving 2979 citations. Previous affiliations of Peter J. Hylands include Kwame Nkrumah University of Science and Technology.
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In vitro tests and ethnopharmacological investigations: Wound healing as an example
TL;DR: Novel findings are the ability of Buddleja globosa leaf extracts to induce differentiation in keratinocytes and to alter the profile of proteins produced by cultured fibroblasts, and investigations into effects on secondary messengers and protein expression.
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The sulphorhodamine (SRB) assay and other approaches to testing plant extracts and derived compounds for activities related to reputed anticancer activity.
TL;DR: The sulphorhodamine B (SRB) assay is described in detail as the preferred method and a novel approach has been developed which is based on the hypothesis that, in some circumstances, the naturally occurring compounds act as prodrugs rather than active compounds in their own right.
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Studies on the biosynthesis of taxol: the taxane carbon skeleton is not of mevalonoid origin
TL;DR: The analysis of long-range 13C13C couplings in taxuyunnanine C obtained from an experiment with [U-13C6]glucose documents the involvement of an intramolecular rearrangement in the biosynthesis of the isoprenoid precursor.
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A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L) ingestion
TL;DR: Although strong intersubject variation in metabolite profiles was observed, clear differentiation between the samples obtained before and after chamomile ingestion was achieved on the basis of increased urinary excretion of hippurate and glycine with depleted creatinine concentration.
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Ethnobotanical survey and cytotoxicity testing of plants of South-western Nigeria used to treat cancer, with isolation of cytotoxic constituents from Cajanus cajan Millsp. leaves.
TL;DR: Most of the species tested had some cytotoxic effect on the cancer cell lines, which to some extent supports their traditional inclusion in herbal preparations for treatment of cancer, which raises concerns over their safety and efficacy in traditional treatment.