Peter Schlattmann

TL;DR: In this paper, the authors systematically searched 15 citation databases for population-level estimates of sepsis incidence rates and fatality in adult populations using consensus criteria and published in the last 36 years.

TL;DR: Age was identified to be an effective modifier of NGAL value with better predictive ability in children and in critically ill patients, and NGAL level was a useful prognostic tool with regard to the prediction of AKI.

TL;DR: A meta-analysis that estimates percentage of infected species based on data on the distribution of infection levels among species using a beta-binomial model and finds that within species the infection frequency follows a ‘most-or-few’ infection pattern.

TL;DR: Procalcitonin is a helpful biomarker for early diagnosis of sepsis in critically ill patients and must be interpreted carefully in the context of medical history, physical examination, and microbiological assessment.

TL;DR: It is confirmed that sepsis is a common and frequently fatal condition affecting neonates and children globally, and few population-based data are available from low-income settings and the lack of standardisation of diagnostic criteria and definition of sepsi in the reviewed studies are obstacles to the accurate estimation of global burden.