P
Ph. Hubert
Researcher at University of Liège
Publications - 69
Citations - 2016
Ph. Hubert is an academic researcher from University of Liège. The author has contributed to research in topics: Solid phase extraction & High-performance liquid chromatography. The author has an hindex of 24, co-authored 67 publications receiving 1794 citations.
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Journal ArticleDOI
Advances in validation, risk and uncertainty assessment of bioanalytical methods.
TL;DR: Several essential aspects of methods validation, not only restricted to chromatographic ones but also to ligand binding assays owing to their increasing role in biopharmaceutical industries are discussed and highlighted.
Journal ArticleDOI
Harmonization of strategies for the validation of quantitative analytical procedures
Ph. Hubert,J.-J. Nguyen-Huu,Bruno Boulanger,E. Chapuzet,Patrice Chiap,N. Cohen,Pierre-Albert Compagnon,Walthère Dewé,Max Feinberg,M. Lallier,M. Laurentie,N. Mercier,G. Muzard,C. Nivet,L. Valat,E. Rozet +15 more
Journal ArticleDOI
Critical review of near-infrared spectroscopic methods validations in pharmaceutical applications.
C. De Bleye,Pierre-François Chavez,Jérôme Mantanus,Roland Djang’eing’a Marini,Ph. Hubert,E. Rozet,Eric Ziemons +6 more
TL;DR: This review gives a comprehensive and critical overview of the methodologies applied to assess the validity of quantitative NIRS methods used in pharmaceutical applications.
Journal ArticleDOI
Data processing of vibrational chemical imaging for pharmaceutical applications
Pierre-Yves Sacre,C. De Bleye,Pierre-François Chavez,Lauranne Netchacovitch,Ph. Hubert,Eric Ziemons +5 more
TL;DR: This review presents fundamental concepts of hyperspectral imaging, the basic theory of the most used chemometric tools used to pre-process, process and post-process the generated data to enable the reader making the best choice among the different tools available.
Journal ArticleDOI
Innovative high-performance liquid chromatography method development for the screening of 19 antimalarial drugs based on a generic approach, using design of experiments, independent component analysis and design space.
Benjamin Debrus,Pierre Lebrun,J. Mbinze Kindenge,J. Mbinze Kindenge,Frédéric Lecomte,Attilio Ceccato,Gabriel Caliaro,J. Mavar Tayey Mbay,Bruno Boulanger,Roland Djang’eing’a Marini,E. Rozet,Ph. Hubert +11 more
TL;DR: A dedicated method for the determination of three antimalarial compounds in a pharmaceutical formulation was optimized to demonstrate both the efficiency and flexibility of the methodology proposed in the present study.