P
Ph. Monnier
Researcher at University Hospital of Lausanne
Publications - 84
Citations - 1778
Ph. Monnier is an academic researcher from University Hospital of Lausanne. The author has contributed to research in topics: Esophagus & Epidermoid carcinoma. The author has an hindex of 25, co-authored 84 publications receiving 1695 citations.
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Journal ArticleDOI
Photodetection and photodynamic therapy of "early" squamous cell carcinomas of the pharynx, oesophagus and tracheo-bronchial tree
Ph. Monnier,Marcel Savary,Ch. Fontolliet,Georges Wagnières,Andre Chatelain,P. Cornaz,C. Depeursinge,H. van den Bergh +7 more
TL;DR: According to these experiments, PDT is efficient at destroying early squamous cell carcinomas in the pharynx, oesophagus and bronchi, but the tumour selectivity of HPD is poor in the digestive tract lined withSquamous cell epithelium, the only hope for the future lies in the synthesis of a more selective and more stable photosensitizer.
Journal ArticleDOI
Clinical determination of tissue optical properties by endoscopic spatially resolved reflectometry.
Roland Bays,Georges Wagnières,D. Robert,Daniel Braichotte,Jean-Francois Savary,Ph. Monnier,H. van den Bergh +6 more
TL;DR: A noninvasive method to measure the optical properties of a diffusing and absorbing medium based on the spatially resolved measurement of diffuse reflectance at the sample surface is described, particularly suitable for investigating the in vivo Optical properties of biological tissues endoscopically in a clinical context.
Journal ArticleDOI
Photodynamic therapy of early squamous cell carcinomas of the esophagus: A review of 31 cases
Jean-Francois Savary,Pierre Grosjean,Ph. Monnier,C. Fontolliet,Georges Wagnières,Daniel Braichotte,H. van den Bergh +6 more
TL;DR: Photodynamic therapy eradicates early squamous cell carcinomas of the esophagus efficiently and was more phototoxic, induced a shorter period of photosensitization of the skin, and had better selectivity than either of the other photosensitizers.
Journal ArticleDOI
Clinical photodynamic therapy for superficial cancer in the oesophagus and the bronchi: 514 nm compared with 630 nm light irradiation after sensitization with Photofrin II.
TL;DR: Results indicate that PDT with 514 nm light has the potential to cure superficial cancer in the oesophagus and bronchi with essentially the same probability of success as red light.
Journal ArticleDOI
Photodynamic therapy for cancer of the upper aerodigestive tract using tetra(m-hydroxyphenyl)chlorin
Pierre Grosjean,Jean-Francois Savary,J. Mizeret,Georges Wagnières,Alain Woodtli,Jean-Francois Theumann,C. Fontolliet,H. van den Bergh,Ph. Monnier +8 more
TL;DR: Photodynamic therapy with mTHPC is a safe and effective technique for the treatment of early carcinomas of the upper aerodigestive tract, but its efficacy is much lower for more advanced cancers.