Phil Chowienczyk

TL;DR: This consensus document advises on the measurement procedures in general and provides arguments for the use of 80% of the direct carotid-femoral distance as the most accurate distance estimate.

TL;DR: Endothelium-dependent vasodilation in response to acetylcholine is impaired in the coronary microvasculature of hypercholesterolaemic subjects, and vasodilator responses to sodium nitroprusside and to methacholine in the forearm resistance vessels are examined, indicating that endothelial dysfunction in hyperCholesterolaemia subjects is generalised and extends to vascular beds outside the coronary circulation.

TL;DR: PWV does not increase during early stages of atherosclerosis, but it does increase in the presence of aortic calcification that occurs within advanced atherosclerotic plaque, and the haemodynamic consequences of increased aorti stiffness are summarized.

TL;DR: The present data show that whole-body production of NO is greater in healthy premenopausal women than in men under ambulatory conditions.

TL;DR: Genistein causes l-arginine/NO-dependent vasodilation in forearm vasculature of human subjects with similar potency to 17&bgr;-estradiol and potentiates endothelium-dependent Vasodilation to acetylcholine.