P
Philip K. Ahring
Researcher at University of Sydney
Publications - 86
Citations - 3826
Philip K. Ahring is an academic researcher from University of Sydney. The author has contributed to research in topics: Receptor & Nicotinic agonist. The author has an hindex of 30, co-authored 82 publications receiving 3564 citations. Previous affiliations of Philip K. Ahring include Nielsen Holdings N.V..
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Journal ArticleDOI
pH Dependency and Desensitization Kinetics of Heterologously Expressed Combinations of Acid-sensing Ion Channel Subunits
TL;DR: Co-expression of three subunits such as ASIC1a+2a+3 and ASIC1b+2 a+3 resulted in data that could best be explained by coexistence of multiple channel populations within the same cell, in good agreement with the fact that ASIC-expressing sensory neurons display a variety of acid-evoked currents.
Journal ArticleDOI
An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo.
Daniel B. Timmermann,Jens Halvard Grønlien,Kathy L. Kohlhaas,Elsebet Ø. Nielsen,Eva Dam,Tino Dyhring Jorgensen,Philip K. Ahring,Dan Peters,Dorte Holst,Jeppe Kejser Christensen,John Malysz,Clark A. Briggs,Murali Gopalakrishnan,Gunnar M. Olsen +13 more
TL;DR: Data support the notion that α7 nAChR allosteric modulation may constitute a novel pharmacological principle for the treatment of cognitive dysfunction.
Journal ArticleDOI
Characterization of the cloned human intermediate-conductance Ca2+-activated K+ channel
Bo Skaaning Jensen,Dorte Strøbæk,Palle Christophersen,Tino Dyhring Jorgensen,Claus Hansen,Asli Silahtaroglu,Asli Silahtaroglu,Søren-Peter Olesen,Philip K. Ahring +8 more
TL;DR: The human intermediate-conductance, Ca2+-activated K+ channel (hIK) was identified by searching the expressed sequence tag database and found to be identical to two recently cloned K+ channels, hSK4 and hIK1.
Journal Article
Correction to An Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor Possessing Cognition-Enhancing Properties in Vivo
D. B. Timmerman,Jens Halvard Grønlien,Kathy L. Kohlhaas,Elsebet Ø. Nielsen,Eva Dam,Tino Dyhring Jorgensen,Philip K. Ahring,Dan Peters,Dorte Holst,Jeppe Kejser Christensen,John Malysz,Clark A. Briggs,Murali Gopalakrishnan,Gunnar M. Olsen +13 more
Journal ArticleDOI
Pharmacological characterization of small‐conductance Ca2+‐activated K+ channels stably expressed in HEK 293 cells
Dorte Strøbæk,Tino Dyhring Jorgensen,Palle Christophersen,Philip K. Ahring,Søren-Peter Olesen +4 more
TL;DR: The pharmacological separation between SK channel subtypes expressed in mammalian cells is too small to support the notion that the apamin‐insensitive afterhyperpolarization of neurones is mediated by hSK1.