P
Philippe Coumel
Researcher at University of Paris
Publications - 18
Citations - 18674
Philippe Coumel is an academic researcher from University of Paris. The author has contributed to research in topics: Long QT syndrome & QT interval. The author has an hindex of 13, co-authored 18 publications receiving 17422 citations.
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Journal ArticleDOI
Heart rate variability: standards of measurement, physiological interpretation and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology.
Alan John Camm,Marek Malik,J. T. Bigger,G. Breithardt,Sergio Cerutti,Richard J. Cohen,Philippe Coumel,Ernest L. Fallen,H.L. Kennedy,Robert E. Kleiger,Federico Lombardi,Alberto Malliani,Arthur J. Moss,Jeffrey N. Rottman,Georg Schmidt,Peter J. Schwartz,D.H. Singer +16 more
Journal ArticleDOI
Genotype-Phenotype Correlation in the Long-QT Syndrome Gene-Specific Triggers for Life-Threatening Arrhythmias
Peter J. Schwartz,Silvia G. Priori,Carla Spazzolini,Arthur J. Moss,G. Michael Vincent,Carlo Napolitano,Isabelle Denjoy,Pascale Guicheney,Günter Breithardt,Mark T. Keating,Jeffrey A. Towbin,Alan H. Beggs,Paul A. Brink,Arthur A.M. Wilde,Lauri Toivonen,Wojciech Zareba,Jennifer L. Robinson,Katherine W. Timothy,Valerie A. Corfield,Duangrurdee Wattanasirichaigoon,Clive Corbett,Wilhelm Haverkamp,Eric Schulze-Bahr,Michael H. Lehmann,Ketty Schwartz,Philippe Coumel,Raffaella Bloise +26 more
TL;DR: Life-threatening arrhythmias in LQTS patients tend to occur under specific circumstances in a gene-specific manner, allowing new insights into the mechanisms that relate the electrophysiological consequences of mutations on specific genes to clinical manifestations and offer the possibility of complementing traditional therapy with gene- specific approaches.
Journal ArticleDOI
Failure in the rate adaptation of the atrial refractory period: its relationship to vulnerability
TL;DR: It is suggested that poor or absent rate adaptation of the atrial refractory period, and a propensity to atrial fibrillation or flutter, constitute a clinical entity not previously described.
Journal ArticleDOI
Notched T Waves on Holter Recordings Enhance Detection of Patients With LQT2 (HERG) Mutations
J. M. Lupoglazoff,Isabelle Denjoy,Myriam Berthet,Nathalie Neyroud,L. Demay,P. Richard,Bernard Hainque,Guy Vaksmann,Didier Klug,Antoine Leenhardt,G. Maillard,Philippe Coumel,Pascale Guicheney +12 more
TL;DR: This study provides novel evidence that Holter recording analysis is superior to the 12-lead ECG in detecting G1 and G2 T-wave notches, with G2 notches being most specific and often reflecting HERG core domain missense mutations.
Journal ArticleDOI
Diagnostic performance of QT interval variables from 24-h electrocardiography in the long QT syndrome
Nathalie Neyroud,P. Maison Blanche,Isabelle Denjoy,S. Chevret,Claire Donger,Eric Dausse,J. Fayn,Fabio Badilini,N. Menhabi,Ketty Schwartz,Pascale Guicheney,Philippe Coumel +11 more
TL;DR: QT interval variables obtained from 24-h ECG recordings improve long QT syndrome diagnosis by showing an increased nocturnal ventricular repolarization rate-dependence in genotyped chromosome 11-linked patients.