P
Philippe Humbert
Researcher at University of Franche-Comté
Publications - 251
Citations - 4905
Philippe Humbert is an academic researcher from University of Franche-Comté. The author has contributed to research in topics: Human skin & Psoriasis. The author has an hindex of 32, co-authored 245 publications receiving 4362 citations. Previous affiliations of Philippe Humbert include French Institute of Health and Medical Research.
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Journal ArticleDOI
Topically applied vitamin C enhances the mRNA level of collagens I and III, their processing enzymes and tissue inhibitor of matrix metalloproteinase 1 in the human dermis.
Betty Nusgens,Philippe Humbert,André Rougier,Alain Colige,Marek Haftek,Charles Lambert,Alain Richard,P. Creidi,Charles M. Lapière +8 more
TL;DR: The results indicate that the functional activity of the dermal cells is not maximal in postmenopausal women and can be increased.
Journal ArticleDOI
Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo.
Philippe Humbert,Marek Haftek,P. Creidi,Charles M. Lapière,Betty Nusgens,Alain Richard,Daniel Schmitt,André Rougier,Hassan Zahouani +8 more
TL;DR: Vitamin C is known for its antioxidant potential and activity in the collagen biosynthetic pathway and Photoprotective properties of topically applied vitamin C have also been demonstrated, placing it as a potential candidate for use in the prevention and treatment of skin ageing.
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Skin ageing: a comparison between Chinese and European populations. A pilot study.
S Nouveau-Richard,Z L Yang,S. Mac-Mary,Li Li,Philippe Bastien,Isabelle Tardy,Claude Bouillon,Philippe Humbert,O. de Lacharrière +8 more
TL;DR: It is shown that main skin ageing features (wrinkles, spots) progress differently in the Chinese and French women studied, and pigmented spot intensity is a much more important ageing sign in Chinese women than in French women.
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Use of amniotic membrane transplantation in the treatment of venous leg ulcers
Isabelle Mermet,Nathalie Pottier,J M Sainthillier,Carole Malugani,Sandrive Cairey-Remonnay,Stéphane Maddens,Didier Riethmuller,Pierre Tiberghien,Philippe Humbert,François Aubin +9 more
TL;DR: AM transplantation seems to function as a safe substrate, promoting proper epithelialization while suppressing excessive fibrosis, and may be considered to be an alternative method for treating chronic leg ulcers.