M
Marek Haftek
Researcher at University of Lyon
Publications - 127
Citations - 3950
Marek Haftek is an academic researcher from University of Lyon. The author has contributed to research in topics: Corneocyte & Stratum corneum. The author has an hindex of 33, co-authored 125 publications receiving 3665 citations. Previous affiliations of Marek Haftek include Claude Bernard University Lyon 1 & French Institute of Health and Medical Research.
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Journal ArticleDOI
Topically applied vitamin C enhances the mRNA level of collagens I and III, their processing enzymes and tissue inhibitor of matrix metalloproteinase 1 in the human dermis.
Betty Nusgens,Philippe Humbert,André Rougier,Alain Colige,Marek Haftek,Charles Lambert,Alain Richard,P. Creidi,Charles M. Lapière +8 more
TL;DR: The results indicate that the functional activity of the dermal cells is not maximal in postmenopausal women and can be increased.
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Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo.
Philippe Humbert,Marek Haftek,P. Creidi,Charles M. Lapière,Betty Nusgens,Alain Richard,Daniel Schmitt,André Rougier,Hassan Zahouani +8 more
TL;DR: Vitamin C is known for its antioxidant potential and activity in the collagen biosynthetic pathway and Photoprotective properties of topically applied vitamin C have also been demonstrated, placing it as a potential candidate for use in the prevention and treatment of skin ageing.
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Refined characterization of corneodesmosin proteolysis during terminal differentiation of human epidermis and its relationship to desquamation.
Michel Simon,Nathalie Jonca,Marina Guerrin,Marek Haftek,Dominique Bernard,Cécile Caubet,Torbjörn Egelrud,Rainer Schmidt,Guy Serre +8 more
TL;DR: Immunoblotting, immunohistochemistry, and immunoelectron microscopy experiments showed that the first step in corneodesmosin processing is the cleavage of its extremities and probably occurs before its incorporation into desmosomes.
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Identification of late differentiation antigens of human cornified epithelia, expressed in re-organized desmosomes and bound to cross-linked envelope.
Guy Serre,Valérie Mils,Marek Haftek,Christian Vincent,Françoise Croute,Alain Reano,J. P. Ouhayoun,Stéphane Bettinger,Jean-Pierre Soleilhavoup +8 more
TL;DR: Late differentiation antigens (Ag) specific for human cornified squamous epithelia, defined by two murine monoclonal antibodies, G36-19 and B17-21, produced after immunization with plantar stratum corneum (SC), are described and are relevant markers for studying desmosomal maturation during epidermal differentiation and desquamation.
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Evidence for a role of corneodesmosin, a protein which may serve to modify desmosomes during cornification, in stratum corneum cell cohesion and desquamation
TL;DR: Results from analyses of nonpalmoplantar stratum corneum suggested that corneodesmosin is degraded in this tissue in a way that may be similar to that in plantar strum corneum, which may be related to the cohesive state of the tissue and to desquamation.