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Philippe Moreau

Researcher at University of Nantes

Publications -  693
Citations -  52995

Philippe Moreau is an academic researcher from University of Nantes. The author has contributed to research in topics: Multiple myeloma & Medicine. The author has an hindex of 104, co-authored 517 publications receiving 42530 citations. Previous affiliations of Philippe Moreau include University of Grenoble & National and Kapodistrian University of Athens.

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Updates on Isatuximab in Relapsed/Refractory and Newly Diagnosed Multiple Myeloma

TL;DR: In the past decade, therapies that are more effective and less toxic have transformed the treatment landscape for patients with MM, but many patients will eventually become refractory to the current haematologic standard of care treatments of proteasome inhibitors, immunomodulatory agents, and mAb therapies.
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First phase 3 results from CARTITUDE-4: Cilta-cel versus standard of care (PVd or DPd) in lenalidomide-refractory multiple myeloma.

TL;DR: CARTITUDE-4 as discussed by the authors is a global, phase 3, randomized, controlled trial (NCT04181827) of ciltacabtagene autoleucel (cilta-cel), a dual-binding, BCMA-targeting CAR-T cell therapy, vs standard of care (SOC), in lenalidomide (len)-refractory patients (pts).