P
Philippe Moreau
Researcher at University of Nantes
Publications - 693
Citations - 52995
Philippe Moreau is an academic researcher from University of Nantes. The author has contributed to research in topics: Multiple myeloma & Medicine. The author has an hindex of 104, co-authored 517 publications receiving 42530 citations. Previous affiliations of Philippe Moreau include University of Grenoble & National and Kapodistrian University of Athens.
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Once weekly versus twice weekly carfilzomib dosing in patients with relapsed and refractory multiple myeloma (A.R.R.O.W.): interim analysis results of a randomised, phase 3 study
Philippe Moreau,Maria-Victoria Mateos,James R. Berenson,Katja Weisel,Antonio Lazzaro,Kevin W. Song,Meletios A. Dimopoulos,Mei Huang,Anita Zahlten-Kumeli,A. Keith Stewart +9 more
TL;DR: Patients with relapsed and refractory multiple myeloma previously treated with two or three treatments, including a proteasome inhibitor and immunomodulatory agent, are recruited from hospital, clinic, oncology or medical centres to compare progression-free survival between groups in the intention-to-treat population.
Journal ArticleDOI
Daratumumab plus lenalidomide and dexamethasone in relapsed/refractory multiple myeloma: extended follow-up of POLLUX, a randomized, open-label, phase 3 study
Nizar J. Bahlis,Meletios A. Dimopoulos,Darrell White,Lotfi Benboubker,Gordon Cook,Merav Leiba,P. Joy Ho,Kihyun Kim,Naoki Takezako,Philippe Moreau,Jonathan L. Kaufman,Maria Krevvata,Christopher Chiu,Xiang Qin,Linda Okonkwo,Sonali Trivedi,Jon Ukropec,Ming Qi,Jesús F. San-Miguel +18 more
TL;DR: Data support using D-Rd in patients with RRMM after first relapse in relapsed/refractory multiple myeloma in POLLUX, and show higher ORR and deeper responses, including complete response or better, than Rd.
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Long-Term Follow-Up of Autotransplantation Trials for Multiple Myeloma: Update of Protocols Conducted by the Intergroupe Francophone du Myelome, Southwest Oncology Group, and University of Arkansas for Medical Sciences
Bart Barlogie,Michel Attal,John Crowley,Frits van Rhee,Jackie Szymonifka,Philippe Moreau,Brian G.M. Durie,Jean-Luc Harousseau +7 more
TL;DR: These long-term follow-up data of transplantation trials provide a crucial framework of reference for outcome reporting of novel agent-based trials reportedly exhibiting remarkable short-term efficacy approaching high-dose therapy results.
Journal ArticleDOI
Peripheral neuropathy and new treatments for multiple myeloma: background and practical recommendations
Bilal Mohty,Jean El-Cheikh,Ibrahim Yakoub-Agha,Philippe Moreau,Jean-Luc Harousseau,Mohamad Mohty +5 more
TL;DR: Early detection of peripheral neuropathy and the use of dose adjustment algorithms as in the case of bortezomib, should help reduce the side effects while maintaining anti-tumor efficacy.
Journal ArticleDOI
Genomic landscape and chronological reconstruction of driver events in multiple myeloma
Francesco Maura,Francesco Maura,Francesco Maura,Niccolo Bolli,Nicos Angelopoulos,Nicos Angelopoulos,Kevin J. Dawson,Daniel Leongamornlert,Inigo Martincorena,Thomas J. Mitchell,Anthony Fullam,Santiago Gonzalez,Raphael Szalat,Federico Abascal,Bernardo Rodriguez-Martin,Mehmet Kemal Samur,Dominik Glodzik,Dominik Glodzik,Marco Roncador,Mariateresa Fulciniti,Yu-Tzu Tai,Stephane Minvielle,Florence Magrangeas,Philippe Moreau,Paolo Corradini,Kenneth C. Anderson,Jose M. C. Tubio,Jose M. C. Tubio,David C. Wedge,Moritz Gerstung,Hervé Avet-Loiseau,Nikhil C. Munshi,Nikhil C. Munshi,Peter J. Campbell +33 more
TL;DR: A catalog and hierarchy of driver lesions using sequences from 67 MM genomes serially collected from 30 patients together with public exome datasets is reported, noting a limited repertoire of initiating driver events that shape the evolutionary trajectory of the disease.