P
Philippe Moreau
Researcher at University of Nantes
Publications - 693
Citations - 52995
Philippe Moreau is an academic researcher from University of Nantes. The author has contributed to research in topics: Multiple myeloma & Medicine. The author has an hindex of 104, co-authored 517 publications receiving 42530 citations. Previous affiliations of Philippe Moreau include University of Grenoble & National and Kapodistrian University of Athens.
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Carfilzomib or bortezomib in relapsed or refractory multiple myeloma (ENDEAVOR): an interim overall survival analysis of an open-label, randomised, phase 3 trial
Meletios A. Dimopoulos,Hartmut Goldschmidt,Ruben Niesvizky,Douglas E. Joshua,Wee Joo Chng,Wee Joo Chng,Albert Oriol,Robert Z. Orlowski,Heinz Ludwig,Thierry Facon,Roman Hájek,Katja Weisel,Vania Hungria,Leonard Minuk,Shibao Feng,Anita Zahlten-Kumeli,Amy S. Kimball,Philippe Moreau +17 more
TL;DR: A stratified log-rank test was used to compare overall survival between treatment groups for this prospectively planned second interim analysis of ENDEAVOR, and progression-free survival was reported to be significantly longer with carfilzomib administered in combination with dexamethasone than with bortezomib and dexamETHasone.
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The phenotype of normal, reactive and malignant plasma cells. Identification of "many and multiple myelomas" and of new targets for myeloma therapy
Régis Bataille,Gaëtan Jego,Nelly Robillard,Sophie Barillé-Nion,Jean-Luc Harousseau,Philippe Moreau,Martine Amiot,Catherine Pellat-Deceunynck +7 more
TL;DR: This review presents data from normal PC up to human myeloma cell lines in order to define different entities of MM based on expression of CD19, CD20, CD27 and CD117; and identify new therapeutic targets.
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Prognostic Significance of Copy-Number Alterations in Multiple Myeloma
Hervé Avet-Loiseau,Cheng Li,Florence Magrangeas,Wilfried Gouraud,Catherine Charbonnel,Jean-Luc Harousseau,Michel Attal,Gerald Marit,Claire Mathiot,Thierry Facon,Philippe Moreau,Kenneth C. Anderson,Loïc Campion,Nikhil C. Munshi,Stephane Minvielle +14 more
TL;DR: A genome-wide analysis of malignant plasma cells from 192 newly diagnosed patients with myeloma using high-density, single-nucleotide polymorphism (SNP) arrays to identify genetic lesions associated with prognosis demonstrated the power and accessibility of molecular karyotyping to predict outcome in myel cancer.
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International Myeloma Working Group Recommendations for the Diagnosis and Management of Myeloma-Related Renal Impairment
Meletios A. Dimopoulos,Pieter Sonneveld,Nelson Leung,Giampaolo Merlini,Heinz Ludwig,Efstathios Kastritis,Hartmut Goldschmidt,Douglas E. Joshua,Robert Z. Orlowski,R. L. Powles,David H. Vesole,Laurent Garderet,Hermann Einsele,Antonio Palumbo,Michele Cavo,Paul G. Richardson,Philippe Moreau,Jesus San Miguel,S. Vincent Rajkumar,B. Durie,Evangelos Terpos +20 more
TL;DR: Recommendations were based on published data through December 2015, and were developed using the system developed by the Grading of Recommendation, Assessment, Development, and Evaluation Working Group.
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Thalidomide for previously untreated elderly patients with multiple myeloma: meta-analysis of 1685 individual patient data from 6 randomized clinical trials
Peter Fayers,Peter Fayers,Antonio Palumbo,Cyrille Hulin,Anders Waage,Pierre W. Wijermans,Meral Beksac,Sara Bringhen,Jean Yves Mary,Peter Gimsing,Fabian Termorshuizen,Rauf Haznedar,Tommaso Caravita,Philippe Moreau,Ingemar Turesson,Pellegrino Musto,Lotfi Benboubker,Martijn R. Schaafsma,Pieter Sonneveld,Thierry Facon +19 more
TL;DR: It is concluded that thalidomide added to MP improves OS and PFS in previously untreated elderly patients with multiple myeloma, extending the median survival time by on average 20%.