P
Phillip J. Walker
Researcher at University of Queensland
Publications - 14
Citations - 781
Phillip J. Walker is an academic researcher from University of Queensland. The author has contributed to research in topics: Aortic aneurysm & Claudication. The author has an hindex of 13, co-authored 14 publications receiving 698 citations. Previous affiliations of Phillip J. Walker include Royal Brisbane and Women's Hospital.
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Journal ArticleDOI
Association of statin prescription with small abdominal aortic aneurysm progression.
Craig D. Ferguson,Paula Clancy,Bernhard Bourke,Phillip J. Walker,Anthony E. Dear,Tim Buckenham,Paul Norman,Jonathan Golledge +7 more
TL;DR: The results do not support the findings of smaller studies and suggest that statin treatment and serum low-density lipoprotein concentrations may have no benefit in reducing AAA progression.
Journal ArticleDOI
Diagnosis and Monitoring of Abdominal Aortic Aneurysm: Current Status and Future Prospects
Joseph V. Moxon,Adam Parr,Theophilus I. Emeto,Phillip J. Walker,Paul Norman,Jonathan Golledge +5 more
TL;DR: The current guidelines for AAA management are outlined and modern scientific techniques currently employed to identify improved diagnostic and prognostic markers are discussed.
Journal ArticleDOI
Fenofibrate increases high-density lipoprotein and sphingosine 1 phosphate concentrations limiting abdominal aortic aneurysm progression in a mouse model
Smriti M. Krishna,Sai Wang Seto,Joseph V. Moxon,Catherine M. Rush,Phillip J. Walker,Paul Norman,Jonathan Golledge +6 more
TL;DR: The present findings suggest that fenofibrate antagonizes AngII-induced AAA and atherosclerosis by up-regulating serum HDL and S1P levels, with associated activation of NO-producing enzymes and reduction of aortic inflammation.
Journal ArticleDOI
A systematic review of studies examining inflammation associated cytokines in human abdominal aortic aneurysm samples
TL;DR: A systematic review of previous studies investigating the relative expression of inflammation associated cytokines within human AAA samples suggests that TNFA and INFG are the most consistently upregulated cytokines in large AAAs.
Journal ArticleDOI
Downregulation of transforming growth factor, beta receptor 2 and Notch signaling pathway in human abdominal aortic aneurysm.
TL;DR: An acquired impairment in TGF-β signaling that along with downregulation of the Notch signaling pathway may contribute to the pathogenesis of AAA.