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Pierangela Ciuffreda

Researcher at University of Milan

Publications -  171
Citations -  1831

Pierangela Ciuffreda is an academic researcher from University of Milan. The author has contributed to research in topics: Lipase & Catalysis. The author has an hindex of 22, co-authored 167 publications receiving 1681 citations. Previous affiliations of Pierangela Ciuffreda include University of Siena & University of Foggia.

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Complete (1)H and (13)C NMR spectral assignment of alpha- and beta-adenosine, 2'-deoxyadenosine and their acetate derivatives.

TL;DR: In this paper, the NMR chemical shifts of adenosine, 2'-deoxyadenosine and their acetate derivatives were completely and definitely assigned using the concerted application of one-and two-dimensional experiments.
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H-Ferritin-nanocaged olaparib: a promising choice for both BRCA-mutated and sporadic triple negative breast cancer.

TL;DR: The findings suggest that H-Ferritin nanoformulation strongly enhances cytotoxic efficacy of Ola as a stand-alone therapy in both BRCA-mutated and wild type TNBC cells, by promoting targeted nuclear delivery.
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Regioselective acylation of 6-deoxy-L- and -D-hexosides through lipase-catalyzed transesterification. Enhanced reactivity of the 4-hydroxy function in the L series

TL;DR: Etude dacylation regioselective par des lipases de Candida cylindracea, Pseudomonas fluorescens provenant du pancreas de porc, des methyl α-L- et α-D-rhamnopyranosides, les methyl α −L − and α −D-fucopyranoides.
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N6-Alkyladenosines: Synthesis and evaluation of in vitro anticancer activity

TL;DR: A series of adenosine analogues differently substituted in N⁶-position were synthesized to continue studies on the relationships between structure and biological activity of iPA and it was found that some of these compounds possess anti-proliferative activity but have no effect on cell invasion and metalloprotease activity.