P
Piergiorgio Gentile
Researcher at Newcastle University
Publications - 124
Citations - 5147
Piergiorgio Gentile is an academic researcher from Newcastle University. The author has contributed to research in topics: Self-healing hydrogels & Chemistry. The author has an hindex of 30, co-authored 106 publications receiving 3714 citations. Previous affiliations of Piergiorgio Gentile include Instituto Politécnico Nacional & Polytechnic University of Turin.
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Journal ArticleDOI
Incorporation of PLGA nanoparticles into porous chitosan-gelatin scaffolds: influence on the physical properties and cell behavior.
Vijay Kumar Nandagiri,Vijay Kumar Nandagiri,Piergiorgio Gentile,Valeria Chiono,Chiara Tonda-Turo,Amos Matsiko,Zeibun Ramtoola,Franco Maria Montevecchi,Gianluca Ciardelli +8 more
TL;DR: In this study, freeze-dried porous chitosan-gelatin scaffolds (CH-G: 1:2 ratio by weight) were embedded with various amounts of poly(lactide-co-glycolide) (PLGA) nanoparticles, and incorporation of PLGA nanoparticles changed the micro-architecture of the scaffolds in terms of mean pore diameter and pore size distribution and increased the compressive modulus.
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Biomimetic hydrogels designed for cartilage tissue engineering
TL;DR: In this paper, the advantages and disadvantages for the manufacturing of biomimetic hydrogels for cartilage regeneration are presented, as well as current limitations and challenges of such hydrogel formulations.
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Process optimisation to control the physico-chemical characteristics of biomimetic nanoscale hydroxyapatites prepared using wet chemical precipitation
TL;DR: In this article, hydroxyapatite nanoscale particles (nHA) were prepared by wet chemical precipitation using four different synthesis methods, and the results showed that the particles obtained were composed of nHA, with different morphologies and aspect ratios (1.5 to 4) and degrees of crystallinity (40% to 70% following calcination) depending on the different process parameters of the synthesis method used, such as temperature, ripening time and pH.
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Functionalised nanoscale coatings using layer-by-layer assembly for imparting antibacterial properties to polylactide-co-glycolide surfaces.
Piergiorgio Gentile,Maria E. Frongia,Mar Cardellach,Cheryl A. Miller,Graham P. Stafford,Graham J. Leggett,Paul V. Hatton +6 more
TL;DR: The antibacterial properties were demonstrated successfully against the keystone periodontal bacteria Porphyromonas gingivalis, which has an influence on implant failure, without compromising in vitro biocompatibility.
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Reinforcement of poly-l-lactic acid electrospun membranes with strontium borosilicate bioactive glasses for bone tissue engineering.
João S. Fernandes,Piergiorgio Gentile,Margarida Isabel Barros Coelho Martins,Nuno M. Neves,Cheryl A. Miller,Aileen Crawford,Ricardo A. Pires,Paul V. Hatton,Rui L. Reis +8 more
TL;DR: The results strongly suggest that the composite PLLA membranes reinforced with the BBG-Sr glass particles have potential as an effective biomaterial capable of promoting bone regeneration.