P
Piero Marchetti
Researcher at Centre national de la recherche scientifique
Publications - 2
Citations - 568
Piero Marchetti is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: U937 cell & Mitochondrial permeability transition pore. The author has an hindex of 2, co-authored 2 publications receiving 561 citations.
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The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death
Tamara Hirsch,Piero Marchetti,Santos S. Susin,Bruno Dallaporta,N Zamzami,Isabel Marzo,Maurice Geuskens,Guido Kroemer +7 more
TL;DR: Electron microscopic analysis confirms that cells treated with PT inducers alone undergo apoptosis, whereas cells kept in identical conditions in the presence of Z-VAD.fmk die from necrosis, compatible with the hypothesis that PT would be a rate limiting step in both the apoptotic and the necrotic modes of cell death.
Journal Article
Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential.
George Rawadi,Sergio Roman-Roman,Maria Castedo,Véronique Dutilleul,Santos A. Susin,Piero Marchetti,Maurice Geuskens,Guido Kroemer +7 more
TL;DR: It is shown that M. fermentans affects the function of human monocytes and myelomonocytic cell lines on at least two different levels and that certain AIDS-associated mycoplasma species perturb the function and/or generation of cells from the myelmonocytic lineage via several distinct pathways.