Pierre Renard

TL;DR: In this article, the authors defined a general formula for the analgesic compounds of general formula (I): ##STR1## in which: R 1, R 2, R 3, R 4, A, Z and m are as defined in the description, their isomers, epimers and diastereoisomers, their addition salts with a pharmaceutically acceptable acid and, when R 1 and R 2 each represent a hydrogen atom, their add salts with an acceptable base.

TL;DR: Novel 6-cyanoindolo[3,2-c]quinoline and 7-cyanobenzimidazoline derivatives have been synthesised by treatment of the appropriate aromatic amines with 4.5-dichloro-1,2,3-dithiazolium chloride 1 (Appel salt).

TL;DR: In this article, a compound of formula (I): Z 1, substituent of the terminal amino group, represents hydrogen, alkyl or acyl, or aryl carbonyl, hetero-carbo-l, aryylalkyl carbonyl, ayrl-oxycarbonyl or alkoxy-carbonyl each of which is optionally substituted, X 1 to X 14 each represents an amino acid residue having the D or L configuration as defined in the description.

TL;DR: In this article, the authors defined compounds of general formula (I): in which R, R1, R2 and R3 are as defined in the description, to their optical isomers, and to their addition salts with a pharmaceutically acceptable base.

TL;DR: In this paper, the authors define a class of compounds of formula (I): for which the values of R, R1, R2 and X are defined in the description, which can be used as medicaments.