P
Pierre Voirol
Researcher at University of Lausanne
Publications - 9
Citations - 141
Pierre Voirol is an academic researcher from University of Lausanne. The author has contributed to research in topics: Citalopram & Antidepressant. The author has an hindex of 5, co-authored 9 publications receiving 136 citations. Previous affiliations of Pierre Voirol include University of California, San Francisco.
Papers
More filters
Journal ArticleDOI
Cytochrome P-450 activities in human and rat brain microsomes.
Pierre Voirol,Michèle Jonzier-Perey,F. Porchet,Marianne J. Reymond,Robert C. Janzer,Constantin Bouras,Henry W. Strobel,Markus Kosel,Chin B. Eap,Pierre Baumann +9 more
TL;DR: It is concluded that cytochrome P450 activity in the brain is very low, but that psychotropic drugs could undergo a local cerebral metabolism which could have pharmacological and/or toxicological consequences.
Journal ArticleDOI
In vitro biotransformation of the selective serotonin reuptake inhibitor citalopram, its enantiomers and demethylated metabolites by monoamine oxidase in rat and human brain preparations.
M. Kosel,C Gnerre,C Gnerre,Pierre Voirol,Pierre Voirol,M. Amey,B Rochat,B Rochat,Constantin Bouras,Bernard Testa,Pierre Baumann +10 more
TL;DR: The biotransformation of citalopram in the rat and human brain occurs mainly through monoamine oxidases and not, as in the liver, through cytochrome P-450.
Journal ArticleDOI
Pharmacokinetic consequences of a citalopram treatment discontinuation.
TL;DR: The pharmacokinetics of citalopram (CIT) were examined in five hospitalized depressed patients after an abrupt discontinuation of a treatment with 40 mg/d of this selective serotonin reuptake inhibitor (SSRI).
Journal ArticleDOI
Serotonin syndrome after small doses of citalopram or sertraline.
Journal ArticleDOI