P
Pilar Alamá
Researcher at University of Valencia
Publications - 35
Citations - 2645
Pilar Alamá is an academic researcher from University of Valencia. The author has contributed to research in topics: Embryo transfer & Endometrium. The author has an hindex of 16, co-authored 29 publications receiving 1766 citations.
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Journal ArticleDOI
A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature
Patricia Diaz-Gimeno,José A. Horcajadas,José Antonio Martínez-Conejero,Francisco J. Esteban,Pilar Alamá,Antonio Pellicer,Carlos Simón +6 more
TL;DR: A genomic tool composed of a customized microarray and a bioinformatic predictor for endometrial dating and to detect pathologies ofendometrial origin can be used clinically in reproductive medicine and gynecology and the transcriptomic signature is a potential endometrian receptivity biomarkers cluster.
Journal ArticleDOI
Evidence that the endometrial microbiota has an effect on implantation success or failure
Inmaculada Moreno,Francisco M. Codoñer,Felipe Vilella,Diana Valbuena,Juan F. Martinez-Blanch,Jorge Jimenez-Almazán,Roberto Alonso,Pilar Alamá,José Remohí,Antonio Pellicer,Daniel Ramón,Carlos Simón +11 more
TL;DR: The results demonstrate the existence of an endometrial microbiota that is highly stable during the acquisition of endometrian receptivity, however, pathological modification of its profile is associated with poor reproductive outcomes for in vitro fertilization patients.
Journal ArticleDOI
Endometrial receptivity is affected in women with high circulating progesterone levels at the end of the follicular phase: a functional genomics analysis
Elena Labarta,José Antonio Martínez-Conejero,Pilar Alamá,José A. Horcajadas,Antonio Pellicer,Carlos Simón,Ernesto Bosch +6 more
TL;DR: The results reveal that elevated progesterone levels on the day of rCG administration can induce significant alterations in the gene expression profile of the endometrium.
Journal ArticleDOI
Single-cell transcriptomic atlas of the human endometrium during the menstrual cycle.
Wanxin Wang,Felipe Vilella,Pilar Alamá,Inmaculada Moreno,Marco Mignardi,Alina Isakova,Wenying Pan,Carlos Simón,Carlos Simón,Stephen R. Quake +9 more
TL;DR: It is discovered that the human window of implantation opens with an abrupt and discontinuous transcriptomic activation in the epithelia, accompanied with a widespread decidualization feature in the stromal fibroblasts.
Journal ArticleDOI
The accuracy and reproducibility of the endometrial receptivity array is superior to histology as a diagnostic method for endometrial receptivity.
Patricia Diaz-Gimeno,Maria Ruiz-Alonso,David Blesa,Nuria Bosch,José Antonio Martínez-Conejero,Pilar Alamá,Nicolás Garrido,Antonio Pellicer,Carlos Simón +8 more
TL;DR: The ERA is more accurate than histologic dating and is a completely reproducible method for the diagnosis of endometrial dating and receptivity status.