P
Ping He
Researcher at Shanghai Jiao Tong University
Publications - 41
Citations - 806
Ping He is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Leptospira & Leptospira interrogans. The author has an hindex of 15, co-authored 36 publications receiving 595 citations.
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Journal ArticleDOI
A Novel Antimicrobial Endolysin, LysPA26, against Pseudomonas aeruginosa.
Mingquan Guo,Chunyan Feng,Jie Ren,Xuran Zhuang,Yan Zhang,Yongzhang Zhu,Ke Dong,Ping He,Xiaokui Guo,Jinhong Qin +9 more
TL;DR: Results show that LysPA26 is a new and promising antimicrobial agent for the combat of Gram-negative pathogens.
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Phage Therapy as a Promising New Treatment for Lung Infection Caused by Carbapenem-Resistant Acinetobacter baumannii in Mice.
Hua Yunfen,Luo Tingting,Luo Tingting,Yiqi Yang,Dong Dong,Rong Wang,Yanjun Wang,Mengsha Xu,Mengsha Xu,Xiaokui Guo,Fupin Hu,Ping He +11 more
TL;DR: Genome sequence and analysis indicated that phage SH-Ab15519 is a novel phage which does not contain the virulence or antibiotic resistance genes and can effectively rescue mice from lethal A. baumannii lung infection without deleterious side effects.
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A Novel Polysaccharide Depolymerase Encoded by the Phage SH-KP152226 Confers Specific Activity Against Multidrug-Resistant Klebsiella pneumoniae via Biofilm Degradation.
Wu Yunqiang,Rong Wang,Mengsha Xu,Yanan Liu,Xianchao Zhu,Jiangfeng Qiu,Qiming Liu,Ping He,Qingtian Li +8 more
TL;DR: Results suggest that combination of the identified novel depolymerase Dep42, encoded by the phage SH-KP152226, with antibiotics may represent a promising strategy to combat infections caused by drug-resistant and biofilm-forming K. pneumoniae.
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Genome-wide transcriptional analysis of temperature shift in L. interrogans serovar lai strain 56601
Jinhong Qin,Jinhong Qin,Yue-Ying Sheng,Zhi-Ming Zhang,Yao-Zhou Shi,Ping He,Bao-Yu Hu,Yang Yang,Shi-Gui Liu,Guoping Zhao,Xiaokui Guo +10 more
TL;DR: Microarray analyses demonstrated that L. interrogans responds globally to temperature alteration and delineate the spectrum of temperature-regulated gene expression in an important human pathogen and provide many new insights into its pathogenesis.
Journal ArticleDOI
In silico and microarray-based genomic approaches to identifying potential vaccine candidates against Leptospira interrogans
Hongliang Yang,Yongzhang Zhu,Yongzhang Zhu,Jinhong Qin,Ping He,Xu-Cheng Jiang,Guoping Zhao,Xiaokui Guo +7 more
TL;DR: 226 genes were identified as vaccine candidates by bioinformatics, CGH and transcriptional analysis on the basis of the theory of reverse vaccinology and these genes are conserved among ten epidemic serovars in China and have high transcriptional levels in vitro.