Piyush Raj

TL;DR: In this article, a broad-spectrum anti-cancer agent acting as a DNA methylation inhibitor is conjugated to 2-cyano-6-aminobenzothiazole and a peptide substrate specific for the tumor-overexpressed enzyme furin, which can self-assemble into nanoparticles that can be detected by CEST MRI.

TL;DR: A large-area and label-free testing platform that combines surface-enhanced Raman spectroscopy and machine learning for the rapid and accurate detection of SARS-CoV-2, and envision that it will offer an important tool for virus detection and future outbreak preparedness.

TL;DR: This study provides a rationale for employing coarse Raman mapping to substantially reduce measurement time thereby enabling the acquisition of reasonably large training datasets that hold the key for label-free single-cell analysis and, consequently, for differentiation of indolent from aggressive phenotypes.

TL;DR: In this paper, a label-free approach featuring diffraction phase imaging and Raman microscopy that can retrieve both morphological and molecular attributes for label free optical phenotyping of individual B cells is presented.

TL;DR: A dual-modal single-antibody approach that synergizes both the intensity and shift of the peak-based immunoassay with Raman enhancement, coined as the INSPIRE assay, is developed for small molecules detection, providing a new and robust strategy for molecular analysis.