Polla Hergert

TL;DR: In mammalian cells, it is found that chromosomes can congress before becoming bioriented, and this congression mechanism depended on the kinetochore-associated, plus end–directed microtubule motor CENP-E (kinesin-7).

TL;DR: It is proposed that loss of centrosome integrity activates a checkpoint that inhibits G1–S progression and satisfies the definition of a checkpoint in having three elements: a perturbation that is sensed, a transducer (p53) and a receiver (p21).

TL;DR: An essential role for Kin Is is revealed in prevention and/or correction of improper kinetochore-microtubule attachments and disruption of MCAK leads to multiple kinetolic, syntelic, and combined merotelic-syntelic attachments.

TL;DR: It is shown that Nuf2 and Hec1 localize throughout the outer plate, and not the corona, of the vertebrate kinetochore, and are part of a stable "core" region whose assembly dynamics are distinct from other outer domain spindle checkpoint and motor proteins.

TL;DR: Laser microsurgery is used to test the hypothesis that attachment of the daughter centriole to the wall of the mother inhibits formation of additional daughters, and proposes that that the size of the PCM cloud associated with the mother centrioles restricts the number of daughters that can form simultaneously.