P
Pratibala Pandit
Researcher at University of Queensland
Publications - 7
Citations - 431
Pratibala Pandit is an academic researcher from University of Queensland. The author has contributed to research in topics: Head and neck squamous-cell carcinoma & DNA methylation. The author has an hindex of 6, co-authored 7 publications receiving 384 citations.
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Journal ArticleDOI
A novel saliva-based microRNA biomarker panel to detect head and neck cancers
Carolina Salazar,Rahul Nagadia,Pratibala Pandit,Justin J. Cooper-White,Nilanjana Banerjee,Nevenka Dimitrova,William B. Coman,Chamindie Punyadeera +7 more
TL;DR: It is shown that a reliable method to isolate miRNAs from small volumes of saliva is developed, and that the saliva-derived mi RNAs miR-9, miR -134 andMiR-191 may serve as novel biomarkers to reliably detect HNSCC.
Journal ArticleDOI
miRNAs in head and neck cancer revisited
TL;DR: The ultimate establishment of miRNA expression profiles that are HNSCC specific, and miRNAs that orchestrate altered gene and protein expression levels in H NSCC, could pave the way for a better understanding of the mechanism underlying its pathogenesis and the development of novel, targeted therapies.
Journal ArticleDOI
Tumor-suppressor Gene Promoter Hypermethylation in Saliva of Head and Neck Cancer Patients.
Dmitry A. Ovchinnikov,Mark E. Cooper,Pratibala Pandit,William B. Coman,Justin J. Cooper-White,Patricia Keith,Ernst J. Wolvetang,Paul D. Slowey,Chamindie Punyadeera +8 more
TL;DR: In this paper, a sensitive methylation-specific polymerase chain reaction (MSP) was used to determine specific methylation events in the promoters of RASSF1A, DAPK1, and p16 genes.
Tumor-suppressor gene promoter hypermethylation in saliva of head and neck cancer patients
Dmitry A. Ovchinnikov,Mark E. Cooper,Pratibala Pandit,William B. Coman,Justin J. Cooper-White,Patricia Keith,Ernst J. Wolvetang,Paul D. Slowey,Chamindie Punyadeera +8 more
TL;DR: In this article, a sensitive methylation-specific polymerase chain reaction (MSP) was used to determine specific methylation events in the promoters of RASSF1A, DAPK1, and p16 genes.
Journal ArticleDOI
High-Yield RNA-Extraction Method for Saliva
TL;DR: In this article, the authors used QIAzolysis reagent (Qiagen) to extract RNA from saliva (both cell-free supernatants and cell pellets), followed by isopropyl alcohol precipitation, cDNA synthesis, and real-time PCR analyses for the genes encoding β-actin (housekeeping) and histatin (a salivary gland-specific gene).