P
Pratik Ghosh
Researcher at Vidyasagar University
Publications - 16
Citations - 490
Pratik Ghosh is an academic researcher from Vidyasagar University. The author has contributed to research in topics: Epitope & Peptide vaccine. The author has an hindex of 5, co-authored 11 publications receiving 293 citations.
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Journal ArticleDOI
Development of epitope-based peptide vaccine against novel coronavirus 2019 (SARS-COV-2): Immunoinformatics approach.
Manojit Bhattacharya,Manojit Bhattacharya,Ashish Ranjan Sharma,Prasanta Patra,Pratik Ghosh,Garima Sharma,Bidhan Chandra Patra,Sang-Soo Lee,Chiranjib Chakraborty,Chiranjib Chakraborty +9 more
TL;DR: To provide a fast immunogenic profile of these epitopes, immunoinformatics analysis is performed so that the rapid development of the vaccine might bring this disastrous situation to the end earlier.
Journal ArticleDOI
A SARS-CoV-2 vaccine candidate: In-silico cloning and validation
Manojit Bhattacharya,Manojit Bhattacharya,Ashish Ranjan Sharma,Prasanta Patra,Pratik Ghosh,Garima Sharma,Bidhan Chandra Patra,Rudra P. Saha,Sang-Soo Lee,Chiranjib Chakraborty,Chiranjib Chakraborty +10 more
TL;DR: The in silico cloning model demonstrated the efficacy of the construct vaccine along with the identified epitopes against SARS-CoV-2 and the vaccine candidate has potent efficacy against COVID-19 infection.
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Exploring the binding efficacy of ivermectin against the key proteins of SARS-CoV-2 pathogenesis: an in silico approach
Abhigyan Choudhury,Nabarun Chandra Das,Ritwik Patra,Manojit Bhattacharya,Pratik Ghosh,Bidhan Chandra Patra,Suprabhat Mukherjee +6 more
TL;DR: In this paper, the possible mechanism of action of ivermectin using in-silico approaches was studied using molecular docking and molecular dynamic simulation, which revealed the candidature of iversectin as an effective drug for treating COVID-19.
Journal ArticleDOI
Designing a next generation multi-epitope based peptide vaccine candidate against SARS-CoV-2 using computational approaches
TL;DR: In this paper, a dual-purpose epitope prediction protocol was designed such that the same epitope elicits both humoral and cellular immune response unlike the earlier designs, and the epitopes predicted were screened against stringent criteria to ensure selection of a potent candidate with maximum antigen coverage and best immune response.
Journal ArticleDOI
A Novel Multi-Epitopic Peptide Vaccine Candidate Against Helicobacter pylori: In-Silico Identification, Design, Cloning and Validation Through Molecular Dynamics
Pratik Ghosh,Swarnav Bhakta,Manojit Bhattacharya,Ashish Ranjan Sharma,Garima Sharma,Sang-Soo Lee,Chiranjib Chakraborty,Chiranjib Chakraborty +7 more
TL;DR: Wang et al. as discussed by the authors developed a novel vaccine construct using B-cell derived T-cell epitopes from four target antigenic proteins (HpaA, FlaA and Omp18), and found the induction of possible immune response using advanced immunoinformatics approaches.