P
Prosper Chonzi
Researcher at University of London
Publications - 37
Citations - 576
Prosper Chonzi is an academic researcher from University of London. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 10, co-authored 27 publications receiving 362 citations. Previous affiliations of Prosper Chonzi include Ministry of Health and Child Welfare.
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Journal ArticleDOI
CYP2B6*6, CYP2B6*18, Body weight and sex are predictors of efavirenz pharmacokinetics and treatment response: population pharmacokinetic modeling in an HIV/AIDS and TB cohort in Zimbabwe
Milcah Dhoro,Simbarashe P. Zvada,Bernard Ngara,Charles Nhachi,Gerald Kadzirange,Prosper Chonzi,Collen Masimirembwa +6 more
TL;DR: Screening for CYP2B6 functional variants has a high predictability for efavirenz plasma levels and could be used in prescribing optimal and safe EFV doses, according to model-based simulations for optimal doses.
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The effect of community-based support for caregivers on the risk of virological failure in children and adolescents with HIV in Harare, Zimbabwe (ZENITH): an open-label, randomised controlled trial
Rashida A. Ferrand,Rashida A. Ferrand,Victoria Simms,Ethel Dauya,Tsitsi Bandason,Grace McHugh,Hilda Mujuru,Prosper Chonzi,Joanna Busza,Katharina Kranzer,Shungu Munyati,Helen A. Weiss,Richard J. Hayes +12 more
TL;DR: Community-based support for caregivers of HIV-infected children and adolescents has high potential for scalability and could have a substantial effect on HIV virological suppression inChildren and adolescents, a group with disproportionately poor treatment outcomes.
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Economic incentives for HIV testing by adolescents in Zimbabwe: a randomised controlled trial
Katharina Kranzer,Victoria Simms,Tsitsi Bandason,Ethel Dauya,Grace McHugh,Shungu Munyati,Prosper Chonzi,Suba Dakshina,Hilda Mujuru,Helen A. Weiss,Rashida A. Ferrand,Rashida A. Ferrand +11 more
TL;DR: Fixed incentives and lottery-based incentives increased the uptake of HIV testing by older children and adolescents, a key hard-to-reach population, and would be sustainable in the context of vertical HIV infection as repeated testing would not be necessary until sexual debut.
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Enhanced adherence counselling and viral load suppression in HIV seropositive patients with an initial high viral load in Harare, Zimbabwe: Operational issues.
Talent Bvochora,Srinath Satyanarayana,Kudakwashe C. Takarinda,Hilda Bara,Prosper Chonzi,Brian Komtenza,Clemence Duri,Tsitsi Apollo +7 more
TL;DR: The routine VL testing levels were high, but there were major programmatic gaps in enrolling PLHIV with high VLs into EAC and achieving VL suppression, suggesting the full potential of EAC on achieving viral load suppression has not been achieved.
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Chronic Morbidity Among Older Children and Adolescents at Diagnosis of HIV Infection
Grace McHugh,Jamie Rylance,Hilda Mujuru,Kusum Nathoo,Prosper Chonzi,Ethel Dauya,Tsitsi Bandason,Victoria Simms,Katharina Kranzer,Rashida A. Ferrand +9 more
TL;DR: In children with slow-progressing HIV, there is a substantial burden of chronic morbidity even when CD4 count is relatively preserved, and timely HIV testing and prompt antiretroviral therapy initiation are urgently needed to prevent development of chronic complications.