Q
Q. Wan
Publications - 4
Citations - 13
Q. Wan is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 1, co-authored 1 publications receiving 4 citations.
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Astragalus polysaccharide alleviates ulcerative colitis by regulating the balance of Tfh/Treg cells.
Youbao Zhong,Qiuping Xiao,Zeng-Ping Kang,Jia-Qi Huang,Wei Ge,Q. Wan,Hai-Yan Wang,Wen Zhou,Hai-Mei Zhao,Duan-Yong Liu +9 more
TL;DR: In this article , dextran sodium sulfate induced mice UC and Astragalus polysaccharide (APS, 200 mg/kg/day) was administered simultaneously, and APS effectively alleviated colitis in mice by improving survival rate, disease activity index (DAI), the change rate of body weight, colonic length and weight, and histopathological injury of the colon.
Journal ArticleDOI
Astragaloside Ⅳ alleviates ulcerative colitis by regulating the balance of Th17/Treg cells.
Youbao Zhong,Wenjun Liu,Yanxia Xiong,Yingmeng Li,Q. Wan,Wen Zhou,Hai-Mei Zhao,Qiuping Xiao,Duan-Yong Liu +8 more
TL;DR: Astragaloside IV (AS-Ⅳ) is a phytochemical naturally occurring in Astragalus membranaceus that has good anti-inflammatory, anti-oxidant and anti-stress properties as discussed by the authors .
Journal ArticleDOI
394 IL-23 Antibodies in Psoriasis – a Non-Clinical Perspective
Journal ArticleDOI
Importance of PLD2 in an IL-23 driven psoriasiform dermatitis model and potential link to human psoriasis.
Zhi Su,Peter F. Slivka,S.E. Paulsboe,Karen Chu,J. Wetter,Marian T. Namovic,Denise Perron,Arun Kannan,Q. Wan,Viktor Todorović,Kathleen M. Smith,Alex Lipovsky,Yibing Wang,Steve McGaraughty,Jacqueline Loud,Victoria E. Scott,Prisca Honore,Eric R. Goedken +17 more
TL;DR: In this article , the role of PLD2 in an interleukin (IL)-23-induced mouse model of psoriasiform dermatitis was explored, and it was shown that PLD1/PLD2 deficiency significantly reduced psoriasis inflammation in IL-23injected ears, as reflected by decreases in ear thickness, expression of defensin beta 4A and the S100 calcium binding protein A7A, macrophage infiltrate, and expression of CXCL10 and IL-6.