Q
Qian Liu
Researcher at Huazhong University of Science and Technology
Publications - 52
Citations - 2604
Qian Liu is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Sudden death & Poison control. The author has an hindex of 17, co-authored 50 publications receiving 1617 citations. Previous affiliations of Qian Liu include Washington University in St. Louis.
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Journal ArticleDOI
Biomarkers for predicting efficacy of PD-1/PD-L1 inhibitors
TL;DR: Biomarkers reflecting tumor immune microenvironment and tumor cell intrinsic features, such as PD-L1 expression, density of tumor infiltrating lymphocyte (TIL), tumor mutational burden, and mismatch-repair (MMR) deficiency, have been noticed to associate with treatment effect of anti-PD-1/anti-PD.
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The CXCL8-CXCR1/2 pathways in cancer
Qian Liu,Anping Li,Yijun Tian,Jennifer D. Wu,Yu Liu,Tengfei Li,Yuan Chen,Xinwei Han,Kongming Wu +8 more
TL;DR: Neovascularisation, which provides a basis for fostering tumour growth and metastasis, is now recognised as a critical function of CXCL8 in the tumour microenvironment and it is proposed that CxCL8 may be a potential therapeutic target for cancer treatment.
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Chimeric antigen receptor T cells: a novel therapy for solid tumors.
TL;DR: The preclinical and clinical progress of CAR-T cells targeting EGFR, human epidermal growth factor receptor 2 (HER2), and mesothelin (MSLN), as well as the challenges forCAR-T cell therapy are summarized.
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EGFR-TKIs resistance via EGFR-independent signaling pathways.
TL;DR: Clinical trials aiming to overcome and prevent TKIs resistance in various cancers are ongoing or completed and EGFR-TKIs in accompany with the targeted agents for resistance-related factors afford a promising first-line strategy to further clinical application.
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Impaired spermatogenesis in COVID-19 patients.
Honggang Li,Xingyuan Xiao,Jie Zhang,Mohammad Ishraq Zafar,Chunlin Wu,Yuting Long,Wei Lu,Feng Pan,Tianqing Meng,Kai Zhao,Liquan Zhou,Shiliang Shen,Liang Liu,Qian Liu,Chengliang Xiong +14 more
TL;DR: Impairment of spermatogenesis was observed in COVID-19 patients, which could be partially explained as a result of an elevated immune response in testis, and autoimmune orchitis occurred in some COVID -19 patients.